Understanding Skyrizi Interactions: Alcohol, Medications, and More

Skyrizi (risankizumab-rzaa) is a prescription medication specifically designed for the management of plaque psoriasis, psoriatic arthritis, and Crohn's disease. Current research indicates that Skyrizi does not have known interactions with alcohol, medications, or dietary supplements. However, it is crucial to avoid live vaccines while undergoing treatment with Skyrizi.

Medical Applications of Skyrizi

Skyrizi is indicated for adults with the following conditions:

• Plaque psoriasis
• Psoriatic arthritis
• Crohn’s disease

Administration of Skyrizi

This medication is available as a liquid solution and can be administered via subcutaneous injection or through intravenous infusion by a healthcare professional. The suffix “-rzaa” in its name distinguishes it from potential future medications with similar compositions.

What Are Drug Interactions?

Drug interactions occur when the effects of one substance are altered by another. Such interactions may also arise from pre-existing health conditions. Continue reading to discover more about the interactions related to Skyrizi.

Possible Drug Interactions with Skyrizi

As of now, there have been no documented drug interactions with Skyrizi. Nevertheless, future interactions may be identified as more patients receive treatment. To mitigate the risk of interactions, it is essential to inform your healthcare provider of all medications, including over-the-counter drugs, vitamins, and supplements you are taking.

Instances to Avoid Skyrizi

Certain health conditions may render Skyrizi inappropriate for specific individuals, a phenomenon known as contraindications. Examples include:

• Allergic Reactions: If you have previously experienced an allergic reaction to Skyrizi or its constituents, it is essential to notify your doctor before starting treatment.

Alcohol and Skyrizi

Currently, Skyrizi is not recognized as interacting with alcohol. However, alcohol consumption might exacerbate the symptoms associated with the conditions it treats. Consulting your healthcare provider about alcohol intake during Skyrizi treatment is advisable.

Additional Interactions with Skyrizi

Skyrizi and Nutritional Supplements

Although no reported interactions exist between Skyrizi and dietary supplements, it remains vital to communicate any supplements you are taking with your healthcare provider. This precaution helps avoid unforeseen interactions.

Skyrizi and Food

No food interactions with Skyrizi have been documented so far. However, consult your healthcare provider if you have dietary concerns during treatment.

Skyrizi and Vaccinations

Patients are advised against receiving live vaccines during Skyrizi treatment due to the potential risk of infection. Common live vaccines include those for chickenpox and measles. Always discuss vaccination plans with your healthcare professional.

Skyrizi and Laboratory Tests

No known interactions with laboratory tests have been reported with Skyrizi. However, if you have upcoming tests, consult your healthcare provider for guidance.

Health History Considerations for Taking Skyrizi

Your medical history can significantly influence the safety of taking Skyrizi. Discuss any relevant conditions with your doctor, including:

• Liver Issues: Treatment with Skyrizi may pose risks for individuals with pre-existing liver conditions, particularly those with Crohn's disease.
• Infections: Concerns about new or progressing infections, including tuberculosis, must be addressed prior to starting Skyrizi.
• Pregnancy and Breastfeeding: The safety of using Skyrizi in pregnant or breastfeeding individuals has not been established. Discuss any plans for pregnancy with your doctor.

Preventing Potential Interactions

To minimize the risk of interactions while on Skyrizi, take the following steps:

• Discuss your alcohol and cannabis use with your healthcare professional.
• Provide a complete list of all medications and supplements you are currently taking, including herbal products.
• Inquire about any new medications you plan to start during treatment.

Understand the medication guide that accompanies Skyrizi. Look for colored labels indicating potential interactions, and ask your pharmacist for comprehensive details if needed.

Using Skyrizi strictly as prescribed is crucial for reducing interaction risks.

Disclaimer: Every effort has been made to ensure the information presented here is accurate and current. However, this content should not replace professional medical advice. Always consult with your healthcare provider before starting any medication. The information contained herein is subject to change and is not exhaustive of all potential uses, directions, precautions, or interactions.