Avomit 10 mg (Tablet)

Unit Price: ৳ 3.50 (15 x 10: ৳ 525.00)
Strip Price: ৳ 35.00

Medicine Details

Category Details
Generic Domperidone maleate
Company Chemist laboratories ltd
Also available as
Avomit 5 mg suspension

Title

Avomit 10 mg Tablet

Category

Medicine

Description

A dopamine antagonist medication used to treat nausea and vomiting

Attributes

  • Indications:
    • Dyspeptic symptom complex
    • Acute nausea and vomiting
    • Parkinson's disease
    • Radiological studies
  • Pharmacology:
    • Dopamine antagonist
    • Blocks dopamine receptors in ChemoreceptorTrigger Zone
    • Gastroprokinetic action
    • Weak penetration across blood-brain barrier
  • Dosage & Administration:
    • Should be taken 15-30 minutes before meals
    • Adult dose: 10-20 mg every 6-8 hours daily
    • Children dose: Based on body weight every 6-8 hours daily
  • Interaction:
    • Anticholinergic drugs antagonize its effect
    • Antacids and antisecretory drugs lower its oral bioavailability
    • Metabolized through CYP3A4
    • Inhibitors may increase plasma levels
  • Contraindications:
    • Known hypersensitivity
    • Neonates
    • Gastrointestinal hemorrhage
    • Mechanical obstruction
    • Prolactin releasing pituitary tumor
  • Side Effects:
    • Transient intestinal cramps
    • Rare extrapyramidal phenomena
    • Increase in plasma prolactin level
    • Rare allergic reactions
  • Pregnancy & Lactation:
    • Use in first trimester if justified
    • Excreted in breast milk
    • Concentrations in breast milk are lower than plasma
  • Precautions & Warnings:
    • Use with caution in children due to risk of extra-pyramidal reactions
    • Use with caution in hepatic impairment
  • Use in Special Populations:
    • Use with caution in infants
    • Use with caution in liver disorders
    • Use with caution in kidney disorders
  • Overdose Effects:
    • Symptoms include drowsiness, disorientation, and extrapyramidal reactions
    • Administration of activated charcoal recommended
  • Therapeutic Class:
    • Motility Stimulants
    • Dopamine antagonist
    • Prokinetic drugs
  • Storage Conditions:
    • Store below 30°C
    • Protected from light & moisture
    • Keep out of children's reach
  • Chemical Structure:
    • Molecular Formula: C22H24ClN5O2
    • Chemical Structure Image: See provided link
  • Common Questions:
    • Used to treat nausea and vomiting
    • Helps relieve nausea, vomiting, and indigestion
    • May cause dizziness and sleepiness
    • Avoid consuming alcohol while taking
    • Dry mouth may occur as a side effect
    • Do not take for longer than 7 days without consulting a doctor

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