Domidon 10 mg (Tablet)
Unit Price: ৳ 3.00 (10 x 10: ৳ 300.00)
Strip Price: ৳ 30.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Domperidone maleate |
| Company | Ziska pharmaceuticals ltd |
| Also available as |
Title
- Domidon 10 mg Tablet
Categories
- Medicine
- Pharmacology
- Gastrointestinal Health
Description
- Domperidone is a dopamine antagonist used to treat dyspeptic symptoms, acute nausea, vomiting, and Parkinson's disease
Dimensions
- Available in 10 mg tablet form
Color options
Functions
- Relieves nausea and vomiting
- Restores normal motility and tone of the upper gastrointestinal tract
- Facilitates gastric emptying
- Enhances antral and duodenal peristalsis
- Regulates contraction of the pylorus
- Increases esophageal peristalsis and lower esophageal sphincter pressure
Materials
Technical specifications
- Molecular Formula: C22H24ClN5O2
Design elements
- Chemical Structure: Image available at the source
Usability features
- Should be taken 15-30 minutes before meals
- Can be taken before retiring
- Should not be taken for longer than 7 days without consulting a doctor
Dosage
- Adults: 10-20 mg (1-2 tablet or 10-20 ml suspension) every 6-8 hours daily
Contraindications
- Known hypersensitivity to the drug
- Neonates
- Patients with gastrointestinal hemorrhage, mechanical obstruction or perforation
- Patients with prolactin releasing pituitary tumor (prolactinoma)
Category
- Motility Stimulants
- Dopamine antagonist
- Prokinetic drugs
Storage conditions
- Store below 30°C
- Protected from light & moisture
- Keep out of children's reach
Pregnancy lactation
- Use during the first trimester if justified by therapeutic benefit
- Not recommended during nursing unless benefits outweigh potential risks
Interaction
- Concomitant administration of anticholinergic drugs may antagonize the antidyspeptic effect of domperidone
- Antacids and antisecretory drugs should not be given simultaneously with domperidone
- Metabolic pathway through CYP3A4, may be affected by inhibitors such as azole antifungals and HIV protease inhibitors
Precautions warnings
- Absolute caution in the case of children due to an increased risk of extra-pyramidal reactions
- Highly metabolized in the liver, caution in patients with hepatic impairment
Special population use
- Caution in infants and under close medical supervision due to immature blood-brain barrier
- Caution in patients with hepatic impairment
- Dosing frequency may need adjustment in patients with severe renal insufficiency
Side effects
- Rare intestinal cramps
- Rare extrapyramidal phenomena
- Possible increase in plasma prolactin level
- Rare allergic reactions such as rash and urticaria
Commonly asked questions
- Used to treat nausea and vomiting
- Helps relieve indigestion
- Should be taken before meals
- May cause dizziness and sleepiness
- Avoid consuming alcohol with this medication
- Dry mouth may occur as a side effect
- Inform doctor if watery diarrhea, fever, or stomach pain persist
Indications
- Relieves dyspeptic symptom complex
- Relieves acute nausea and vomiting
- Can be used in Parkinson's disease
- Aids in radiological studies for speeding barium transit
Pharmacology
- Dopamine antagonist
- Blocks dopamine receptors in the Chemoreceptor Trigger Zone (CTZ) and stomach
- Restores normal motility and tone of the upper gastrointestinal tract
- Facilitates gastric emptying
- Enhances antral and duodenal peristalsis
Overdose effects
- Symptoms may include drowsiness, disorientation, and extrapyramidal reactions
- Activated charcoal can be administered
- Close observation is recommended