Dompa 10 mg (Tablet)
Unit Price: ৳ 2.00 (10 x 10: ৳ 200.00)
Strip Price: ৳ 20.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Domperidone maleate |
| Company | Seema pharmaceuticals ltd |
| Also available as |
Title
- Dompa 10 mg Tablet
Categories
- Medications
- Gastrointestinal Drugs
- Prokinetic Agents
Description
- Dopamine antagonist medication
- Used to treat dyspeptic symptom complex
- Also used for acute nausea and vomiting
- Effective for Parkinson's disease-induced nausea and vomiting
DosageAndAdministration
- Should be taken 15-30 minutes before meals
- Usual recommended oral dose for adults: 10-20 mg every 6-8 hours daily
- Maximum dose for adults: 80 mg daily
- Dosage for children should be based on body weight
- Rectal administration for certain cases
Pharmacology
- Dopamine antagonist
- Blocks dopamine receptors in Chemoreceptor Trigger Zone and stomach
- Restores normal motility and tone of upper gastrointestinal tract
- Enhances antral and duodenal peristalsis
- Increases esophageal peristalsis and lower esophageal sphincter pressure
Interaction
- Anticholinergic drugs may antagonize the effect of domperidone
- Antacids and antisecretory drugs should not be given simultaneously
- Metabolism through CYP3A4
- Potential influence on absorption of concomitantly orally administered drugs
Contraindications
- Known hypersensitivity to the drug
- Neonates
- Dangerous gastrointestinal stimulation scenarios
SideEffects
- Rare side effects include transient intestinal cramps
- Rare extrapyramidal phenomena, particularly in young children
- Possible increase in plasma prolactin level
- Rare allergic reactions such as rash and urticaria
PregnancyAndLactation
- Use in first trimester if justified by anticipated therapeutic benefit
- No evidence of increased risk of malformations in humans
- Not recommended during breastfeeding
- Does not affect mental alertness
PrecautionsAndWarnings
- Use with caution in children due to risk of extra-pyramidal reactions
- Use with caution in patients with hepatic impairment
SpecialPopulations
- Use in infants with great caution and under close medical supervision
- Use with caution in patients with liver or kidney disorders
- Regular review for patients on prolonged therapy
OverdoseEffects
- Symptoms may include drowsiness and disorientation
- Close observation and administration of activated charcoal recommended
- Anticholinergic or antiparkinson drugs may be helpful
TherapeuticClass
- Motility Stimulants
- Dopamine Antagonist
- Prokinetic Drugs
StorageConditions
- Store below 30°C
- Protected from light and moisture
- Keep out of children's reach
ChemicalStructure
- Molecular Formula: C22H24ClN5O2
- Chemical Structure Image: [Link to image]
CommonlyAskedQuestions
- Used to treat nausea and vomiting
- Should be taken before meals as per doctor's prescription
- May cause dizziness and sleepiness
- Alcohol consumption should be avoided
- Dry mouth may occur as a side effect
- Doctor consultation required for prolonged use