Dopagut 10 mg (Tablet)

Unit Price: ৳ 3.00 (10 x 10: ৳ 300.00)
Strip Price: ৳ 30.00

Medicine Details

Category Details
Generic Domperidone maleate
Company Concord pharmaceuticals ltd
Also available as
Dopagut 5 mg suspension

Title

  • Dopagut 10 mg Tablet

Categories

  • Medicine
  • Pharmaceutical

Description

  • A dopamine antagonist medication used for treating nausea and vomiting

Available Colors

  • N/A

Dimensions

  • N/A

Dosage Form

  • Tablet
  • Suspension
  • Paediatric drops
  • Suppositories

Dosage Instructions

  • Should be taken 15-30 minutes before meals
  • Adults: 10-20 mg (1-2 tablets), every 6-8 hours daily
  • Children: 2-4 ml suspension/10 kg body weight, every 6-8 hours daily

Recommended Usage

  • Adults: For dyspeptic symptoms - 10-20 mg, every 6-8 hours daily
  • Children: For dyspeptic symptoms - 0.2-0.4 mg/kg body weight
  • Adults: In acute nausea and vomiting - 20 mg, every 6-8 hours daily
  • Children: In acute nausea and vomiting - 0.2-0.4 mg/kg body weight
  • Rectal use: Adults - 30-60 mg every 4-8 hours
  • Rectal use: Children - Maximum daily dose is 30 mg for 10 to 25 kg

Pharmacology

  • Dopamine antagonist
  • Blocks dopamine receptors in the ChemoreceptorTrigger Zone (CTZ) and stomach
  • Restores normal motility and tone of the upper gastrointestinal tract
  • Facilitates gastric emptying
  • Enhances antral and duodenal peristalsis

Contraindications

  • Known hypersensitivity to the drug
  • Neonates
  • Gastrointestinal stimulation might be dangerous

Interaction

  • Anticholinergic drugs may antagonize the effect
  • Antacids and antisecretory drugs should not be given simultaneously
  • Inhibition of CYP3A4 enzyme may increase plasma levels

Side Effects

  • Transient intestinal cramps
  • Extrapyramidal phenomena in rare cases
  • Increase in plasma prolactin level
  • Rare cases of allergic reactions such as rash and urticaria

Pregnancy & Lactation

  • Use during first trimester if justified by therapeutic benefit
  • Excreted in breast milk, concentration in breast milk is 4 times lower than plasma
  • Nursing not recommended unless benefits outweigh potential risks

Precautions

  • Use with caution in children due to risk of extra-pyramidal reactions
  • Highly metabolized in the liver, caution in patients with hepatic impairment

Overdose Effects

  • Symptoms may include drowsiness, disorientation, and extrapyramidal reactions
  • Administration of activated charcoal recommended
  • Anticholinergic or antihistamines with anticholinergic properties may be helpful

Therapeutic Class

  • Motility Stimulants
  • Dopamine antagonist
  • Prokinetic drugs

Storage Conditions

  • Store below 30°C
  • Protected from light & moisture
  • Keep out of children's reach

Chemical Structure

  • Molecular Formula: C22H24ClN5O2

Commonly Asked Questions

  • Used to treat nausea and vomiting
  • Relieves nausea, vomiting, and indigestion
  • May cause dizziness and sleepiness
  • Avoid consuming alcohol while taking the medication
  • Inform your doctor if you experience persistent symptoms

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