Doridon 5 mg/ml (Pediatric Drops)
15 ml drop: ৳ 25.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Domperidone maleate |
| Company | Medicon pharmaceuticals ltd |
| Also available as |
Title
- Doridon 5 mg/ml Pediatric Drop
Categories
- Medicine
- Pharmaceutical
Description
- Dopamine antagonist medication for relief from nausea and vomiting
- Also used for dyspeptic symptom complex, acute nausea and vomiting, Parkinson's disease, and radiological studies
Dimensions
- Available in 5 mg/ml concentration for pediatric use
Color Options
- Transparent liquid
Functions
- Relieves nausea and vomiting
- Restores normal motility and tone of the upper gastrointestinal tract
- Facilitates gastric emptying
- Enhances antral and duodenal peristalsis
- Regulates contraction of the pylorus
- Increases esophageal peristalsis
- Elevates lower esophageal sphincter pressure
Materials
- Active ingredient: Domperidone
- Chemical structure: C22H24ClN5O2
Technical Specifications
- Molecular Formula: C22H24ClN5O2
- Storage conditions: Below 30°C, protected from light & moisture
Design Elements
- Transparent packaging
- Pediatric-specific dosing guidance
- Chemical structure diagram included
Usability Features
- Comes in suspension form for easy administration to children
Dosage & Administration
- Should be taken 15-30 minutes before meals
- Maximum daily dose for adults is 80 mg
- Different dosing regimens for dyspeptic symptom, acute and sub-acute conditions, and rectal administration
Interaction
- Antagonized by anticholinergic drugs
- Not to be given simultaneously with antacids and antisecretory drugs
- Main metabolic pathway is through CYP3A4
- In vitro data suggest potential interactions with CYP3A4 inhibitors and orally administered drugs
Contraindications
- Hypersensitivity to the drug
- Neonates
- Gastrointestinal hemorrhage, mechanical obstruction or perforation
- Prolactin releasing pituitary tumor
Side Effects
- Rare instances of transient intestinal cramps
- Rare extrapyramidal phenomena in adults
- Possible increase in plasma prolactin level leading to galactorrhoea and gynaecomastia
- Rare allergic reactions like rash and urticaria
Pregnancy & Lactation
- Limited use during first trimester if justified by therapeutic benefit
- Excreted in breast milk with lower concentration than plasma
- Potential risks during nursing
Precautions & Warnings
- Caution in children due to risk of extra-pyramidal reactions
- Caution in patients with hepatic impairment
Use in Special Populations
- Great caution in infants under 1 year of age
- Caution in patients with hepatic impairment
- Review needed for patients on prolonged therapy
Overdose Effects
- Symptoms include drowsiness, disorientation, and extrapyramidal reactions
- Recommended treatment includes activated charcoal and close observation
Therapeutic Class
- Motility Stimulants
- Motility stimulants/Dopamine antagonist
- Prokinetic drugs
Commonly Asked Questions
- Usage for relieving nausea, vomiting, and indigestion
- Tips for usage and precautions
Chemical Structure
- Molecular Formula: C22H24ClN5O2
- Chemical Structure included
Storage Conditions
- Store below 30°C
- Protected from light & moisture
- Keep out of children's reach