Dudon 5 mg/5 ml (Oral Suspension)
60 ml bottle: ৳ 30.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Domperidone maleate |
| Company | Kumudini pharma ltd |
| Also available as |
Title
- Dudon 5 mg/5 ml Suspension
Categories
- Medicine
- Healthcare
- Pharmaceuticals
Description
- Dopamine antagonist medication for treating nausea and vomiting
- Gastroprokinetic action on the motility of the gastrointestinal tract
Indications
- Epigastric sense of fullness
- Feeling of abdominal distension
- Upper abdominal pain
- Eructation
- Flatulence
- Early satiety
- Nausea and vomiting
- Heartburn with or without regurgitations of gastric contents in the mouth
- Non-ulcer dyspepsia
- Acute nausea and vomiting
- Parkinson's disease
- Radiological studies
Pharmacology
- Dopamine antagonist
- Blocks dopamine receptors in the ChemoreceptorTrigger Zone (CTZ) and stomach
- Restores normal motility and tone of the upper gastrointestinal tract
- Facilitates gastric emptying
- Enhances antral and duodenal peristalsis
- Regulates contraction of the pylorus
- Increases esophageal peristalsis and lower esophageal sphincter pressure
Dosage & Administration
- Should be taken 15-30 minutes before meals
- Usual recommended oral dose for adults: 10-20 mg every 6-8 hours daily
- Maximum dose of 80 mg daily
- Dosage for children based on body weight and condition
Interactions
- Antagonized by anticholinergic drugs
- Lower oral bioavailability when given with antacids and antisecretory drugs
- Main metabolic pathway through CYP3A4
- Potential interaction with drugs that inhibit CYP3A4
- May influence absorption of concomitantly orally administered drugs
Contraindications
- Known hypersensitivity to the drug
- Neonates
- Gastrointestinal hemorrhage, mechanical obstruction, or perforation
- Prolactin releasing pituitary tumor (prolactinoma)
Side Effects
- Transient intestinal cramps
- Extrapyramidal phenomena
- Increased plasma prolactin level
- Rare allergic reactions like rash and urticaria
Pregnancy & Lactation
- Should be used with caution during the first trimester of pregnancy
- Excreted in breast milk
- Not recommended during nursing unless benefits outweigh risks
Precautions & Warnings
- Increased risk of extra-pyramidal reactions in young children
- Caution in patients with hepatic impairment
Use in Special Populations
- Caution in infants and under close medical supervision
- Caution in patients with hepatic or renal impairment
Overdose Effects
- Drowsiness
- Disorientation
- Extrapyramidal reactions
- Recommendation of activated charcoal and close observation
Therapeutic Class
- Motility Stimulants
- Dopamine antagonist
- Prokinetic drugs
Storage Conditions
- Store below 30°C, protected from light & moisture
Chemical Structure
- Molecular Formula: C22H24ClN5O2
Common Questions about Dudon 5 mg/5 ml Suspension
- Used for treating nausea and vomiting
- Relieves indigestion
- Should be taken before meals
- May cause dizziness and sleepiness
- Avoid consuming alcohol
- Dry mouth may occur as a side effect
- Do not take for longer than 7 days without consulting a doctor