Egut 5 mg/5 ml (Oral Suspension)

60 ml bottle: ৳ 40.00

Medicine Details

Category Details
Generic Domperidone maleate
Company Euro pharma ltd
Also available as

Indications

  • Dyspeptic symptom complex
  • Delayed gastric emptying
  • Gastroesophageal reflux
  • Esophagitis
  • Acute nausea and vomiting
  • Parkinson's disease
  • Radiological studies

Pharmacology

  • Dopamine antagonist
  • ChemoreceptorTrigger Zone (CTZ) blocking
  • Gastroprokinetic action
  • Gastrointestinal motility
  • Blood-brain barrier penetration
  • Gastric emptying facilitator
  • Esophageal peristalsis regulation
  • Pylorus contraction regulator

Dosage & Administration

  • Oral administration
  • Time of administration (before meals)
  • Adult dosage range
  • Children dosage range
  • Rectal administration
  • Maximum daily dose
  • Suppository dosage

Interaction

  • Anticholinergic drug interaction
  • Oral bioavailability reduction
  • Metabolic pathway (CYP3A4)
  • CYP3A4 inhibitors
  • Influence on drug absorption
  • Interaction with neuroleptics
  • Interaction with dopaminergic agonists

Contraindications

  • Known hypersensitivity
  • Neonatal use
  • Gastrointestinal hemorrhage
  • Mechanical obstruction
  • Perforation
  • Prolactin releasing pituitary tumor

Side Effects

  • Intestinal cramps
  • Extrapyramidal phenomena
  • Prolactin level increase
  • Neuroendocrinological phenomena
  • Allergic reactions

Pregnancy & Lactation

  • Teratogenic effects in animals
  • First trimester use
  • Excretion in breast milk
  • Breast milk concentration
  • Effects on newborn
  • Effects on ability to drive

Precautions & Warnings

  • Children risk caution
  • Extra-pyramidal reactions risk
  • Hepatic impairment caution

Use in Special Populations

  • Infant use caution
  • Liver disorders caution
  • Kidney disorders caution
  • Renal insufficiency dosing adjustment

Overdose Effects

  • Drowsiness
  • Disorientation
  • Extrapyramidal reactions
  • Activated charcoal
  • Anticholinergic drugs use

Therapeutic Class

  • Motility Stimulants
  • Dopamine antagonist
  • Prokinetic drugs

Storage Conditions

  • Temperature range (below 30°C)
  • Protection from light & moisture
  • Child safety

Chemical Structure

  • Molecular Formula: C22H24ClN5O2
  • Chemical Structure Image: Chemical Structure of Domperidone

Common Questions about Egut 5 mg/5 ml Suspension

  • Therapeutic use
  • Relief of nausea, vomiting, and indigestion
  • Dose and duration guidance
  • Dizziness and sleepiness caution
  • Alcohol consumption caution
  • Dry mouth management
  • Reporting adverse effects
  • Duration of use caution

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