Fixgut 5 mg/5 ml (Oral Suspension)

60 ml bottle: ৳ 36.00

Medicine Details

Category Details
Generic Domperidone maleate
Company Apex pharmaceuticals ltd
Also available as
Fixgut 10 mg tablet

Title

Fixgut 5 mg/5 ml Suspension

Categories

  • Medicine
  • Dopamine Antagonist
  • Prokinetic Drug
  • Motility Stimulant

Description

Fixgut 5 mg/5 ml Suspension is used to treat dyspeptic symptom complex, acute nausea and vomiting, Parkinson's disease, and to speed up barium transit in radiological studies. It works by blocking dopamine receptors in the Chemoreceptor Trigger Zone, stomach, and gastrointestinal tract to regulate motility, facilitate gastric emptying, and prevent regurgitation.

Color options

  • Clear

Dimensions

  • Volume: 5 ml

Functions

  • Relieves nausea and vomiting
  • Improves dyspeptic symptoms
  • Facilitates gastric emptying
  • Enhances gastrointestinal motility

Materials

  • Domperidone
  • Maleate

Technical specifications

  • Molecular formula: C22H24ClN5O2

Design elements

  • Suspension
  • Oral dosage form

Usability features

  • Prevents early satiety
  • Relieves heartburn
  • Speeds up barium transit in radiological studies
  • Recommended to be taken 15-30 minutes before meals

Dosage and administration

  • Adults:
    • 10-20 mg every 6-8 hours daily
    • Maximum dose of 80 mg daily
  • Children:
    • 2-4 ml suspension/10 kg body weight every 6-8 hours
    • Maximum period of treatment is 12 weeks

Interaction

  • Antagonistic drugs:
    • Anticholinergic drugs
  • Bioavailability lowering drugs:
    • Antacids
    • Antisecretory drugs
  • Metabolic pathway: CYP3A4

Contraindications

  • Hypersensitivity to the drug
  • Neonates
  • Gastrointestinal hemorrhage
  • Mechanical obstruction
  • Perforation
  • Prolactin releasing pituitary tumor

Side effects

  • Transient intestinal cramps
  • Extrapyramidal phenomena
  • Hyperprolactinaemia
  • Allergic reactions like rash and urticaria

Pregnancy and lactation

  • Pregnancy: Use in the first trimester justified by therapeutic benefit
  • Lactation: Not recommended unless benefits outweigh potential risks

Precautions and warnings

  • Children: Use with absolute caution due to risk of extra-pyramidal reactions
  • Hepatic impairment: Use with caution due to high metabolism in the liver

Special populations

  • Infants: Use with caution and under close medical supervision due to immature blood-brain barrier
  • Liver disorders: Use with caution due to high metabolism in liver
  • Kidney disorders: Dosing frequency may need to be reduced in severe renal insufficiency

Overdose effects

  • Drowsiness
  • Disorientation
  • Extrapyramidal reactions

Therapeutic class

Motility Stimulants/Dopamine antagonist

Storage conditions

Store below 30°C, Protected from light & moisture

Common questions

  • What is Fixgut 5 mg/5 ml Suspension used for?

Related Brands