Gutset 10 mg (Tablet)
Unit Price: ৳ 4.00 (10 x 10: ৳ 400.00)
Strip Price: ৳ 40.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Domperidone maleate |
| Company | Ad din pharmaceuticals ltd |
| Also available as |
Product Title
- Gutset 10 mg Tablet
Indications
- Dyspeptic symptom complex
- Delayed gastric emptying
- Gastroesophageal reflux
- Esophagitis
- Acute nausea and vomiting
- Parkinson's disease
- Radiological studies
Pharmacology
- Dopamine antagonist
- ChemoreceptorTrigger Zone (CTZ) antagonist
- Gastroprokinetic action
- Gastrointestinal motility regulation
- Facilitates gastric emptying
- Enhances peristalsis
- Regulates pyloric contraction
Dosage & Administration
- Taken 15-30 minutes before meals
- Oral dose for adults and children
- Rectal administration for adults and children
- Maximum dose for adults and children
- Duration of treatment
Interaction
- Antagonism by anticholinergic drugs
- Decreased bioavailability with antacids/antisecretory drugs
- Metabolic pathway through CYP3A4
- Potential inhibition by CYP3A4 inhibitors
- Possible influence on absorption of concomitant orally administered drugs
Contraindications
- Known hypersensitivity
- Neonates
- Gastrointestinal hemorrhage
- Mechanical obstruction or perforation
- Prolactin releasing pituitary tumor
Side Effects
- Transient intestinal cramps
- Rare extrapyramidal phenomena
- Increase in plasma prolactin level
- Hyperprolactinaemia effects
- Rare allergic reactions such as rash and urticaria
Pregnancy & Lactation
- Use during first trimester if justified by therapeutic benefit
- No evidence of increase in risk of malformations in humans
- Excretion in breast milk
- Effects on ability to drive and use machines
Precautions & Warnings
- Caution in children for increased risk of extrapyramidal reactions
- Caution in hepatic impairment due to high metabolism in liver
Use in Special Populations
- Caution in infants due to immature blood-brain barrier
- Caution in liver disorders
- Caution in kidney disorders due to increased elimination half-life
Overdose Effects
- Symptoms
- Recommended actions in case of overdosage
- Use of anticholinergic, antiparkinson drugs or antihistamines for controlling extrapyramidal reactions
Therapeutic Class
- Motility Stimulants
- Dopamine antagonist
- Prokinetic drugs
Storage Conditions
- Store below 30°C
- Protected from light & moisture
- Keep out of children's reach
Chemical Structure
- Molecular Formula
- Chemical Structure
Common Questions
- Usage
- Quick Tips