Motigut 5 mg/ml (Pediatric Drops)
Medicine Details
| Category | Details |
|---|---|
| Generic | Domperidone maleate |
| Company | Square pharmaceuticals plc |
| Also available as |
Title
Motigut 5 mg/ml Pediatric Drop
Categories
- Medicine
- Gastrointestinal Medication
- Pediatric Medication
Description
Motigut 5 mg/ml Pediatric Drop is a dopamine antagonist medication mainly used to treat nausea, vomiting, and dyspeptic symptom complex. It acts as a motility stimulant and is primarily indicated for conditions like delayed gastric emptying, gastroesophageal reflux, Parkinson's disease, and acute nausea and vomiting. Its pharmacological action involves blocking dopamine receptors in the Chemoreceptor Trigger Zone (CTZ) and stomach, which restores normal motility and tone of the upper gastrointestinal tract, facilitates gastric emptying, and enhances antral and duodenal peristalsis. The recommended dosage varies for adults and children depending on the condition being treated, and it should be administered with caution in special populations like infants and individuals with hepatic or renal impairment. Domperidone, the active ingredient, is contraindicated in patients with known hypersensitivity to the drug and in neonates, and it may have interactions with certain drugs such as anticholinergics and CYP3A4 inhibitors.