Motil 10 mg (Tablet)
Medicine Details
| Category | Details |
|---|---|
| Generic | Domperidone maleate |
| Company | Hallmark pharmaceuticals ltd |
| Also available as |
Indications
- Dyspeptic symptom complex
- Acute nausea and vomiting
- Parkinson's disease
- Radiological studies
Pharmacology
Blocks dopamine receptors, restores normal motility and tone of upper GI tract, facilitates gastric emptying, enhances peristalsis, increases esophageal peristalsis and lower esophageal sphincter pressure
Dosage & Administration
- Should be taken 15-30 minutes before meals and, if necessary, before retiring
- Adults: 10-20 mg every 6-8 hours daily
- Children: 2-4 ml suspension/10 kg body weight every 6-8 hours daily
Interaction
Concomitant administration of anticholinergic drugs may antagonize the antidyspeptic effect of domperidone
Contraindications
Known hypersensitivity, neonates, gastrointestinal hemorrhage, mechanical obstruction, perforation, prolactin releasing pituitary tumor
Side Effects
- Transient intestinal cramps
- Extrapyramidal phenomena
- Increase in plasma prolactin level
- Allergic reactions such as rash and urticaria
Pregnancy & Lactation
Should only be used during the first trimester of pregnancy if justified, excreted in breast milk, not recommended for nursing mothers
Precautions & Warnings
Use with caution in children, hepatic impairment
Use in Special Populations
- Use with caution in infants
- Use with caution in liver disorders
- Use with caution in kidney disorders
Overdose Effects
Symptoms may include drowsiness, disorientation, extrapyramidal reactions
Therapeutic Class
Motility Stimulants, Dopamine antagonist, Prokinetic drugs
Storage Conditions
Store below 30°C, protected from light & moisture
Chemical Structure
- Molecular Formula: C22H24ClN5O2
- Chemical Structure: https://medex.com.bd/storage/res/g-res-380-domperidone-maleate-chemical-structure-4Q6P0Z8laWrV7xnOkSMm.svg
Common Questions about Motil 10 mg Tablet
- Used for treating nausea and vomiting
- Helps relieve nausea, vomiting, and indigestion
- May cause dizziness and sleepiness, avoid alcohol intake, inform doctor if experiencing certain side effects