Normogut 5 mg/5 ml (Oral Suspension)
100 ml bottle: ৳ 40.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Domperidone maleate |
| Company | Rangs pharmaceuticals ltd |
| Also available as |
Title
- Normogut 5 mg/5 ml Suspension
Categories
- Medicine
- Healthcare
- Pharmaceuticals
Indications
- Dyspeptic symptom complex
- Delayed gastric emptying
- Gastroesophageal reflux
- Esophagitis
- Acute nausea and vomiting
- Parkinson's disease
- Radiological studies
Pharmacology
- Dopamine antagonist
- ChemoreceptorTrigger Zone (CTZ) blocker
- Gastroprokinetic action
- Restores normal motility and tone of upper gastrointestinal tract
DosageAndAdministration
- Should be taken 15-30 minutes before meals
- Usual recommended oral dose for adults and children
- Rectal administration for adults and children
Interaction
- Concomitant administration of anticholinergic drugs may antagonize the antidyspeptic effect
- Antacids and antisecretory drugs should not be given simultaneously
- Main metabolic pathway of domperidone is through CYP3A4
- Potentiation and suppression of actions of other drugs
Contraindications
- Known hypersensitivity to the drug
- Neonates
- Gastrointestinal hemorrhage, obstruction, or perforation
- Prolactin releasing pituitary tumor
SideEffects
- Transient intestinal cramps
- Extrapyramidal phenomena
- Increase in plasma prolactin level
- Rare allergic reactions like rash and urticaria
PregnancyAndLactation
- Use during first trimester justified by therapeutic benefit
- No evidence of increase in risk of malformations in humans
- Excreted in breast milk of lactating rats
PrecautionsAndWarnings
- Caution in the case of children
- Increased risk of extra-pyramidal reactions in young children
- Caution in patients with liver and kidney disorders
UseInSpecialPopulations
- Caution in infants
- Use in liver disorders
- Use in kidney disorders
- Review of patients on prolonged therapy
OverdoseEffects
- Symptoms of overdosage
- Recommendations for management of overdosage
TherapeuticClass
- Motility Stimulants
- Dopamine antagonist
- Prokinetic drugs
StorageConditions
- Store below 30°C
- Protected from light and moisture
- Keep out of children's reach
CompoundSummary
- Molecular Formula
- C22H24ClN5O2
- Chemical Structure
CommonQuestions
- Uses of Normogut 5 mg/5 ml Suspension
- Quick Tips for Taking Normogut 5 mg/5 ml Suspension