Omid 5 mg/5 ml (Oral Suspension)

60 ml bottle: ৳ 28.00

Medicine Details

Category Details
Generic Domperidone maleate
Company Desh pharmaceuticals ltd
Also available as
Omid 10 mg tablet

Title

  • Omid 5 mg/5 ml Suspension

Category

  • Dopamine Antagonist Medication
  • Prokinetic Drug
  • Motility Stimulant

Description

  • Dyspeptic Symptom Complex Relief
  • Acute Nausea and Vomiting Treatment
  • Parkinson's Disease Management
  • Radiological Studies Aid

Color Options

  • Clear liquid suspension

Dosage Form

  • Liquid suspension

Dosage Instructions

  • Take 15-30 minutes before meals
  • Adults: 10-20 mg (1-2 tablets or 10-20 ml suspension), every 6-8 hours daily
  • Children: 2-4 ml suspension/10 kg body weight every 6-8 hours daily
  • Maximum dose of 80 mg daily for adults
  • Treatment duration varies based on condition

Administration Routes

  • Oral
  • Rectal (suppositories)

Pharmacology

  • Dopamine antagonist
  • Blocks dopamine receptors in Chemoreceptor Trigger Zone (CTZ) and stomach
  • Restores normal motility and tone of upper gastrointestinal tract
  • Facilitates gastric emptying
  • Enhances antral and duodenal peristalsis
  • Regulates contraction of the pylorus
  • Increases esophageal peristalsis and lower esophageal sphincter pressure
  • Weak penetration across the blood-brain barrier

Interaction

  • Antagonized by anticholinergic drugs
  • Antacids and antisecretory drugs lower oral bioavailability
  • Metabolized primarily through CYP3A4
  • Potential interaction with CYP3A4 inhibitors
  • May influence absorption of orally administered drugs
  • No influence on blood levels of digoxin or paracetamol

Contraindications

  • Known hypersensitivity to the drug
  • Neonates
  • Gastrointestinal hemorrhage, mechanical obstruction, or perforation
  • Prolactin releasing pituitary tumor (prolactinoma)

Side Effects

  • Rare transient intestinal cramps
  • Rare extrapyramidal phenomena
  • Increase in plasma prolactin level
  • Possible neuroendocrinological phenomena like galactorrhea and gynecomastia
  • Rare allergic reactions such as rash and urticaria

Pregnancy & Lactation

  • Use during the first trimester if justified by anticipated therapeutic benefit
  • No evidence of increased risk of malformations in humans
  • Excreted in breast milk at lower concentrations compared to plasma
  • Nursing not recommended unless benefits outweigh potential risk

Precautions & Warnings

  • Absolute caution in children due to risk of extrapyramidal reactions
  • Use with caution in patients with hepatic impairment

Special Populations

  • Use in infants with caution and under close medical supervision
  • Use with caution in liver disorders and kidney disorders

Overdose Effects

  • Symptoms may include drowsiness, disorientation, and extrapyramidal reactions
  • Recommended treatment includes administration of activated charcoal and close patient observation

Therapeutic Class

  • Motility Stimulants
  • Dopamine Antagonist
  • Prokinetic Drugs

Storage Conditions

  • Store below 30°C
  • Protected from light and moisture
  • Keep out of children's reach

Chemical Structure

  • Molecular Formula: C22H24ClN5O2
  • Chemical Structure Image URL: https://medex.com.bd/storage/res/g-res-380-domperidone-maleate-chemical-structure-4Q6P0Z8laWrV7xnOkSMm.svg

Common Questions

  • Uses for nausea and vomiting relief
  • Tips for usage, side effects, and precautions

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