Ridon EG 10 mg/sachet (Effervescent Granules)

10 mg sachet: ৳ 6.00 (30's pack: ৳ 180.00)

Medicine Details

Category Details
Generic Domperidone maleate
Company Eskayef pharmaceuticals ltd
Also available as
Ridon 10 mg tablet Ridon 5 mg suspension Ridon fast 10 mg tablet

Title

Ridon EG 10 mg/sachet Eff. Granules

Categories

  • Medicine
  • Gastrointestinal Health
  • Nausea and Vomiting Relief
  • Parkinson's Disease Management
  • Radiological Studies

Description

Dopamine antagonist medication primarily used for treating symptoms like dyspepsia, nausea, vomiting, and delayed gastric emptying

DosageAndAdministration

  • Should be taken 15-30 minutes before meals
  • Adults: 10-20 mg (1-2 tablet or 10-20 ml suspension), every 6-8 hours daily
  • Children: 2-4 ml suspension/10 kg body weight, every 6-8 hours daily

Usability

  • Relieves nausea, vomiting, and indigestion
  • Enhances gastric emptying
  • Facilitates esophageal peristalsis and lower esophageal sphincter pressure

TechnicalSpecifications

  • Molecular Formula: C22H24ClN5O2

ChemicalStructure

https://medex.com.bd/storage/res/g-res-380-domperidone-maleate-chemical-structure-4Q6P0Z8laWrV7xnOkSMm.svg

Indications

  • Treats dyspeptic symptom complex like epigastric fullness, abdominal distension, upper abdominal pain
  • Manages acute nausea and vomiting of functional, organic, or induced origins
  • Effective in dopamine-agonist induced nausea and vomiting in Parkinson's disease
  • Speeds barium transit in follow-through radiological studies

Pharmacology

Dopamine antagonist that blocks receptors in Chemoreceptor Trigger Zone and stomach, restoring normal gastrointestinal motility and tone

Interaction

  • Anticholinergic drugs may antagonize the antidyspeptic effect
  • Antacids and antisecretory drugs should not be given simultaneously
  • Metabolized via CYP3A4 pathway, so caution with inhibitors like azole antifungals and HIV protease inhibitors
  • Does not potentiate action of neuroleptics or dopaminergic agonists

Contraindications

  • Known hypersensitivity to the drug
  • Neonates, gastrointestinal hemorrhage, mechanical obstruction, or perforation
  • Prolactin releasing pituitary tumor (prolactinoma)

SideEffects

  • Transient intestinal cramps
  • Rare extrapyramidal phenomena
  • Possible increase in plasma prolactin levels
  • Rare allergic reactions like rash and urticaria

PregnancyAndLactation

  • Use during the first trimester justified by therapeutic benefit
  • Not recommended during breastfeeding unless potential benefits outweigh risks

PrecautionsAndWarnings

  • Use with caution in children and hepatic impairment patients

SpecialPopulations

  • Use with caution in infants due to immature blood-brain barrier
  • Caution in liver disorders and reduced dosing frequency in severe renal insufficiency

OverdoseEffects

  • Symptoms may include drowsiness, disorientation, and extrapyramidal reactions
  • Activated charcoal and close observation recommended in case of overdose

TherapeuticClass

Motility Stimulants, Motility stimulants/Dopamine antagonist, Prokinetic drugs

StorageConditions

Store below 30°C, Protected from light & moisture, Keep out of children's reach

CommonQuestions

  • Used to treat nausea, vomiting, and indigestion
  • Should be taken before meals as per the prescribed dose and duration
  • May cause dizziness and sleepiness; avoid driving or consuming alcohol

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