Vegadon 10 mg (Tablet)
Unit Price: ৳ 2.00 (10 x 10: ৳ 200.00)
Strip Price: ৳ 20.00
Medicine Details
Category | Details |
---|---|
Generic | Domperidone maleate |
Company | Pharmasia limited |
Also available as |
Product title
- Vegadon 10 mg Tablet
Categories
- Medicine
- Pharmaceutical
Dosage form
- Tablet
- Suspension
- Paediatric Drops
- Suppositories
Indication
- Dyspeptic symptom complex
- Delayed gastric emptying
- Gastroesophageal reflux
- Esophagitis
- Acute nausea and vomiting
- Parkinson's disease
- Radiological studies
Pharmacology
- Dopamine antagonist
- Gastroprokinetic action
- Restores normal motility and tone of upper gastrointestinal tract
Dosage recommendation
- 10-20 mg for adults
- 2-4 ml suspension/10 kg body weight for children
- 20 mg for acute and sub-acute conditions
- 30-60 mg rectally for adults
- Maximum daily dose of 80 mg
Interaction
- Contraindicated with anticholinergic drugs
- Lowered oral bioavailability with antacids and antisecretory drugs
- Metabolism through CYP3A4
- Inhibition by azole antifungals, macrolide antibiotics, HIV protease inhibitors
Contraindications
- Known hypersensitivity to the drug
- Neonates
- Dangerous gastrointestinal stimulation
- Gastrointestinal hemorrhage
- Mechanical obstruction or perforation
- Prolactin releasing pituitary tumor (prolactinoma)
Side effects
- Transient intestinal cramps
- Extrapyramidal phenomena
- Increase in plasma prolactin level
- Allergic reactions like rash and urticaria
Pregnancy and lactation
- Use during first trimester if justified by therapeutic benefit
- No evidence of increase in risk of malformations in humans
- Excretion in breast milk of lactating rats
- Not recommended for nursing mothers unless expected benefits outweigh potential risk
Precautions and warnings
- Absolute caution in use for children
- Increased risk of extrapyramidal reactions in young children
- Use with caution in hepatic impairment
Special populations
- Caution in infants due to incomplete development of blood-brain barrier
- Use with caution in liver disorders
- Use with caution in severe renal insufficiency
Overdose effects
- Drowsiness
- Disorientation
- Extrapyramidal reactions
- Activated charcoal administration recommended
Therapeutic class
- Motility Stimulants
- Dopamine antagonist
- Prokinetic drugs
Storage conditions
- Store below 30°C
- Protected from light & moisture
- Keep out of children's reach
Chemical structure
- Molecular Formula: C22H24ClN5O2
Common questions
- Used for treating nausea and vomiting
- Relieves nausea, vomiting and indigestion
- Caution for driving or activities requiring mental focus
- Avoid alcohol consumption
- Possible side effect of dry mouth
- Consult doctor if watery diarrhea, fever, or stomach pain persists
- Do not take for longer than 7 days without consulting a doctor