Vegadon 10 mg (Tablet)

Unit Price: ৳ 2.00 (10 x 10: ৳ 200.00)
Strip Price: ৳ 20.00

Medicine Details

Category Details
Generic Domperidone maleate
Company Pharmasia limited
Also available as

Product title

  • Vegadon 10 mg Tablet

Categories

  • Medicine
  • Pharmaceutical

Dosage form

  • Tablet
  • Suspension
  • Paediatric Drops
  • Suppositories

Indication

  • Dyspeptic symptom complex
  • Delayed gastric emptying
  • Gastroesophageal reflux
  • Esophagitis
  • Acute nausea and vomiting
  • Parkinson's disease
  • Radiological studies

Pharmacology

  • Dopamine antagonist
  • Gastroprokinetic action
  • Restores normal motility and tone of upper gastrointestinal tract

Dosage recommendation

  • 10-20 mg for adults
  • 2-4 ml suspension/10 kg body weight for children
  • 20 mg for acute and sub-acute conditions
  • 30-60 mg rectally for adults
  • Maximum daily dose of 80 mg

Interaction

  • Contraindicated with anticholinergic drugs
  • Lowered oral bioavailability with antacids and antisecretory drugs
  • Metabolism through CYP3A4
  • Inhibition by azole antifungals, macrolide antibiotics, HIV protease inhibitors

Contraindications

  • Known hypersensitivity to the drug
  • Neonates
  • Dangerous gastrointestinal stimulation
  • Gastrointestinal hemorrhage
  • Mechanical obstruction or perforation
  • Prolactin releasing pituitary tumor (prolactinoma)

Side effects

  • Transient intestinal cramps
  • Extrapyramidal phenomena
  • Increase in plasma prolactin level
  • Allergic reactions like rash and urticaria

Pregnancy and lactation

  • Use during first trimester if justified by therapeutic benefit
  • No evidence of increase in risk of malformations in humans
  • Excretion in breast milk of lactating rats
  • Not recommended for nursing mothers unless expected benefits outweigh potential risk

Precautions and warnings

  • Absolute caution in use for children
  • Increased risk of extrapyramidal reactions in young children
  • Use with caution in hepatic impairment

Special populations

  • Caution in infants due to incomplete development of blood-brain barrier
  • Use with caution in liver disorders
  • Use with caution in severe renal insufficiency

Overdose effects

  • Drowsiness
  • Disorientation
  • Extrapyramidal reactions
  • Activated charcoal administration recommended

Therapeutic class

  • Motility Stimulants
  • Dopamine antagonist
  • Prokinetic drugs

Storage conditions

  • Store below 30°C
  • Protected from light & moisture
  • Keep out of children's reach

Chemical structure

  • Molecular Formula: C22H24ClN5O2

Common questions

  • Used for treating nausea and vomiting
  • Relieves nausea, vomiting and indigestion
  • Caution for driving or activities requiring mental focus
  • Avoid alcohol consumption
  • Possible side effect of dry mouth
  • Consult doctor if watery diarrhea, fever, or stomach pain persists
  • Do not take for longer than 7 days without consulting a doctor

Related Brands