Xepadon 5 mg/5 ml (Oral Suspension)

60 ml bottle: ৳ 25.00

Medicine Details

Title

  • Xepadon 5 mg/5 ml Suspension

Categories

  • Medicine
  • Pharmaceuticals

Description

  • Dyspeptic symptom relief
  • Nausea and vomiting treatment
  • Parkinson's disease management
  • Radiological studies facilitation

Color Options

  • Clear liquid

Dosage Form

  • Suspension

Dosage Administration

  • Should be taken 15-30 minutes before meals
  • Adults: 10-20 mg every 6-8 hours
  • Children: 2-4 ml suspension/10 kg body weight
  • Maximum daily dose: 80 mg

Pharmacology

  • Dopamine antagonist
  • Blocks dopamine receptors in Chemoreceptor Trigger Zone (CTZ) and stomach
  • Enhances gastric emptying and peristalsis
  • Increases esophageal peristalsis and lower esophageal sphincter pressure

Interaction

  • Antagonistic effect with anticholinergic drugs
  • Lowered oral bioavailability with antacids and antisecretory drugs
  • Metabolic pathway via CYP3A4
  • Possible influence on absorption of concomitantly administered drugs

Contraindications

  • Known hypersensitivity to domperidone
  • Neonates
  • Gastrointestinal hemorrhage, obstruction, or perforation
  • Prolactin releasing pituitary tumor

Side Effects

  • Rare intestinal cramps
  • Extrapyramidal phenomena in rare cases
  • Possible increase in plasma prolactin level
  • Rare allergic reactions

Pregnancy & Lactation

  • Use in first trimester justified by therapeutic benefit
  • Excreted in breast milk
  • Concentrations in breast milk lower than plasma
  • Effect on ability to drive and use machines: None

Precautions & Warnings

  • Increased risk of extrapyramidal reactions in young children
  • Caution in patients with hepatic impairment

Use in Special Populations

  • Caution in infants due to immature blood-brain barrier
  • Caution in hepatic impairment
  • Dosage adjustment may be needed in severe renal insufficiency

Overdose Effects

  • Drowsiness and disorientation
  • Extrapyramidal reactions, especially in children
  • Recommendations: Activated charcoal, close observation, anticholinergic drugs

Therapeutic Class

  • Motility Stimulants
  • Dopamine antagonist
  • Prokinetic drugs

Storage Conditions

  • Store below 30°C
  • Protected from light & moisture
  • Keep out of children's reach

Chemical Structure

  • Molecular Formula: C22H24ClN5O2

Common Questions

  • What is it used for?: Treats nausea and vomiting
  • Quick Tips:
    • Relieves nausea, vomiting, and indigestion
    • Avoid alcohol consumption
    • Caution while driving or doing activities requiring mental focus

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