Xepadon 5 mg/5 ml (Oral Suspension)
60 ml bottle: ৳ 25.00
Medicine Details
Category | Details |
---|---|
Generic | Domperidone maleate |
Company | Amico laboratories ltd |
Also available as |
Title
- Xepadon 5 mg/5 ml Suspension
Categories
- Medicine
- Pharmaceuticals
Description
- Dyspeptic symptom relief
- Nausea and vomiting treatment
- Parkinson's disease management
- Radiological studies facilitation
Color Options
- Clear liquid
Dosage Form
- Suspension
Dosage Administration
- Should be taken 15-30 minutes before meals
- Adults: 10-20 mg every 6-8 hours
- Children: 2-4 ml suspension/10 kg body weight
- Maximum daily dose: 80 mg
Pharmacology
- Dopamine antagonist
- Blocks dopamine receptors in Chemoreceptor Trigger Zone (CTZ) and stomach
- Enhances gastric emptying and peristalsis
- Increases esophageal peristalsis and lower esophageal sphincter pressure
Interaction
- Antagonistic effect with anticholinergic drugs
- Lowered oral bioavailability with antacids and antisecretory drugs
- Metabolic pathway via CYP3A4
- Possible influence on absorption of concomitantly administered drugs
Contraindications
- Known hypersensitivity to domperidone
- Neonates
- Gastrointestinal hemorrhage, obstruction, or perforation
- Prolactin releasing pituitary tumor
Side Effects
- Rare intestinal cramps
- Extrapyramidal phenomena in rare cases
- Possible increase in plasma prolactin level
- Rare allergic reactions
Pregnancy & Lactation
- Use in first trimester justified by therapeutic benefit
- Excreted in breast milk
- Concentrations in breast milk lower than plasma
- Effect on ability to drive and use machines: None
Precautions & Warnings
- Increased risk of extrapyramidal reactions in young children
- Caution in patients with hepatic impairment
Use in Special Populations
- Caution in infants due to immature blood-brain barrier
- Caution in hepatic impairment
- Dosage adjustment may be needed in severe renal insufficiency
Overdose Effects
- Drowsiness and disorientation
- Extrapyramidal reactions, especially in children
- Recommendations: Activated charcoal, close observation, anticholinergic drugs
Therapeutic Class
- Motility Stimulants
- Dopamine antagonist
- Prokinetic drugs
Storage Conditions
- Store below 30°C
- Protected from light & moisture
- Keep out of children's reach
Chemical Structure
- Molecular Formula: C22H24ClN5O2
Common Questions
- What is it used for?: Treats nausea and vomiting
- Quick Tips:
- Relieves nausea, vomiting, and indigestion
- Avoid alcohol consumption
- Caution while driving or doing activities requiring mental focus