Xepadon 5 mg/ml (Pediatric Drops)
15 ml drop: ৳ 18.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Domperidone maleate |
| Company | Amico laboratories ltd |
| Also available as |
Product Title
- Xepadon 5 mg/ml Pediatric Drop
Categories
- Medicine
- Pharmaceuticals
Description
- Dopamine antagonist used for treating dyspeptic symptom complex, acute nausea and vomiting, Parkinson's disease, and speeding barium transit in radiological studies.
Dosage & Administration
- Should be taken 15-30 minutes before meals
- Adults: 10-20 mg every 6-8 hours daily, maximum 80 mg daily
- Children: 2-4 ml suspension/10 kg body weight every 6-8 hours daily
- Rectal administration: Adults 30-60 mg every 4-8 hours, Children maximum 30 mg for those weighing 10-25 kg
Indications
- Dyspeptic symptom complex
- Acute nausea and vomiting
- Parkinson's disease
- Radiological studies
Pharmacology
- Dopamine antagonist
- Blocks dopamine receptors in Chemoreceptor Trigger Zone and stomach
- Restores normal motility and tone of upper gastrointestinal tract
- Facilitates gastric emptying
- Enhances antral and duodenal peristalsis
- Increases esophageal peristalsis
- Regulates contraction of the pylorus
Interaction
- Contraindicated with anticholinergic drugs
- Do not administer simultaneously with antacids and antisecretory drugs
- Metabolized through CYP3A4
- May interact with CYP3A4 inhibitors like azole antifungals, macrolide antibiotics, HIV protease inhibitors
Contraindications
- Known hypersensitivity to the drug
- Neonates
- Gastrointestinal hemorrhage, mechanical obstruction, perforation
- Prolactin releasing pituitary tumor (prolactinoma)
Side Effects
- Rare intestinal cramps
- Rare extrapyramidal phenomena in young children and adults
- Possible increase in plasma prolactin level
- Rare allergic reactions like rash and urticaria
Pregnancy & Lactation
- Use in first trimester if justified
- Excreted in breast milk
- Not recommended for nursing mothers unless benefits outweigh potential risk
Precautions & Warnings
- Use with caution in children due to risk of extra-pyramidal reactions
- Use with caution in patients with hepatic impairment
Use in Special Populations
- Use with caution in infants due to immature blood-brain barrier
- Use with caution in patients with hepatic impairment
- Use with caution in patients with severe renal insufficiency
Overdose Effects
- Symptoms may include drowsiness, disorientation, extrapyramidal reactions
- Administration of activated charcoal and close observation recommended
- Anticholinergic, antiparkinson drugs may be helpful in controlling extrapyramidal reactions
Therapeutic Class
- Motility Stimulants/Dopamine antagonist
- Prokinetic drugs
Storage Conditions
- Store below 30°C
- Protected from light & moisture
- Keep out of children's reach
Chemical Structure
- Molecular Formula: C22H24ClN5O2
Common Questions
- Used to treat nausea and vomiting
- Should be taken before meals
- May cause dizziness and sleepiness
- Avoid consuming alcohol while taking the medicine
- Inform your doctor about any adverse effects
Common Questions Tips
- Helps relieve nausea, vomiting, and indigestion
- May cause dizziness and sleepiness
- Dry mouth may occur as a side effect
- Do not take for longer than 7 days without consulting your doctor