Canasa 400 mg (Tablet (Delayed Release))

Unit Price: ৳ 5.00 (3 x 10: ৳ 150.00)
Strip Price: ৳ 50.00

Medicine Details

Category Details
Generic Mesalazine 5 aminosalicylic acid
Company Drug international ltd

Title

  • Canasa

Category

  • Medicine
  • Pharmaceutical

Indications

  • Treatment of mild to moderately active Ulcerative Colitis & Crohn's Disease
  • Maintenance of remission of Ulcerative Colitis
  • Maintenance of remission of Crohn's disease

Pharmacology

  • Mechanism of action is unknown
  • Appears to be topical rather than systemic
  • Diminishes inflammation by blocking cyclooxygenase and inhibiting prostaglandin production in the colon

Dosage & Administration

  • Adult dosage: Up to 4 gm mesalazine once daily or divided into 2-4 doses for active disease
  • Adult maintenance dosage: 2 gm mesalazine once daily
  • Pediatric dosage: To be determined individually based on age and weight
  • Granules must not be chewed, and the contents of the sachet should be emptied onto the tongue and washed down with water or orange juice

Interaction

  • Concurrent use of nephrotoxic agents such as NSAIDs and Azathioprine may increase the risk of renal reactions

Contraindications

  • Hypersensitivity to salicylates or any other component of the formulation

Side Effects

  • Headache
  • Nausea
  • Dizziness
  • Asthenia
  • Dyspepsia
  • Vomiting
  • Pruritus

Pregnancy & Lactation

  • Should be given in pregnancy only if the potential benefit justifies the potential risk to the fetus
  • Caution advised when administered to a nursing mother

Precautions & Warnings

  • Patients with pyloric stenosis may have prolonged gastric retention of Mesalamine tablets
  • Renal impairment, including minimal change nephropathy and acute and chronic interstitial nephritis reported in patient

Use in Special Populations

  • Geriatric patients should have blood cell counts closely monitored during Mesalamine therapy
  • Elderly patients are more likely to have decreased renal function
  • Safety and effectiveness in pediatric patients not established

Overdose Effects

  • No specific antidote for Mesalamine overdose
  • Treatment for suspected acute severe toxicity should be symptomatic and supportive

Therapeutic Class

  • Aminosalicylates

Storage Conditions

  • Store below 30 0 C
  • Protect from light and moisture
  • Keep out of reach of children

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