Augment 250 mg+125 mg (Tablet)

Unit Price: ৳ 25.00 (3 x 6: ৳ 450.00)
Strip Price: ৳ 150.00

Medicine Details

Category Details
Generic Amoxicillin clavulanic acid
Company Eskayef pharmaceuticals ltd
Also available as
Augment 500 mg tablet Augment 875 mg tablet Augment 125 mg suspension Augment 1 gm injection

Indications

  • Short-term treatment of bacterial infections
  • Upper respiratory tract infections
  • Lower respiratory tract infections
  • Genito-urinary tract infections
  • Skin and soft tissue infections
  • Bone and joint infections
  • Antibacterial properties
  • Bactericidal activity
  • Microorganism susceptibility
  • Septic abortion treatment

Composition

  • 375 mg tablet
  • 625 mg tablet
  • 1 gm tablet
  • Powder for Suspension
  • Powder for Suspension (Forte)
  • 1.2 gm Injection
  • 0.6 gm injection
  • Amoxicillin content
  • Clavulanic Acid content
  • Film coated tablet

Pharmacology

  • Antibiotic combination
  • Bactericidal activity
  • Broad spectrum of activity
  • Microorganism susceptibility
  • Pharmacokinetics
  • Serum levels
  • Absorption optimization

Dosage

  • Adult dosage
  • Children dosage
  • Tablet dosage
  • Suspension dosage
  • Injection dosage
  • Oral administration
  • IV administration
  • Treatment duration
  • Increased dosage for severe infections

Administration

  • Oral dosage form
  • IV injection
  • Intravenous administration
  • Intramuscular administration
  • Subcutaneous administration
  • Gastrointestinal tolerance
  • Injection duration

Interaction

  • Prolongation of bleeding time
  • Prothrombin time effects
  • Efficacy reduction with oral contraceptives
  • Concomitant use with allopurinol
  • Allergic skin reactions

Contraindications

  • Penicillin hypersensitivity
  • Cross-sensitivity with beta-lactam antibiotics
  • History of cholestatic jaundice

Side Effects

  • Diarrhoea
  • Pseudomembranous colitis
  • Indigestion
  • Nausea
  • Vomiting
  • Candidiasis
  • Hepatitis
  • Cholestatic jaundice
  • Urticarial rashes
  • Erythematous rashes
  • Angioedema
  • Anaphylaxis

Pregnancy & Lactation

  • Teratogenic effect in animal studies
  • Limited use in human pregnancy
  • Breast milk transmission

Precautions & Warnings

  • Anticoagulation therapy
  • Severe hepatic dysfunction
  • Renal impairment
  • Fluid intake maintenance
  • Urinary output maintenance
  • Hepatic function monitoring

Use in Special Populations

  • Dose adjustment for renal impairment
  • Hepatic impairment caution

Overdose Effects

  • Gastrointestinal symptoms
  • Fluid and electrolyte balance disturbance
  • Haemodialysis for removal

Therapeutic Class

  • Broad spectrum penicillins

Reconstitution

  • IV injection reconstitution
  • Dissolving the powder in Water for Injection BP
  • Incompatible reconstitution fluids

Storage Conditions

  • Temperature requirement
  • Light and moisture protection
  • Refrigeration of reconstituted suspension
  • Reconstituted vial usage duration

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