Besectil 20 mg (Capsule (Enteric Coated))

Unit Price: ৳ 4.00 (100's pack: ৳ 400.00)

Medicine Details

Category Details
Generic Omeprazole
Company Bengal drugs ltd

Indications

  • Gastric and duodenal ulcer
  • NSAID-associated duodenal and gastric ulcer
  • Prophylaxis in patients with a history of NSAID-associated duodenal and gastric ulcer
  • Gastro-esophageal reflux disease
  • Long-term management of acid reflux disease
  • Acid-related dyspepsia
  • Severe ulcerating reflux esophagitis
  • Prophylaxis of acid aspiration during general anesthesia
  • Zollinger-Ellison syndrome
  • Helicobacter pylori-induced peptic ulcer

Pharmacology

  • Inhibitor of gastric acid secretion
  • Action on hydrogen-potassium-adenosine triphosphatase (H+/K+ ATPase) enzyme system
  • Onset of antisecretory effect occurs within one hour
  • Maximum effect occurs within two hours
  • Inhibition of secretion lasts up to 72 hours
  • Return of secretory activity after discontinuation of the drug

Dosage

  • Dosage for benign gastric and duodenal ulcer
  • Dosage for NSAID-associated duodenal or gastric ulcer
  • Dosage for gastro-esophageal reflux disease
  • Dosage for long-term management of acid reflux disease
  • Dosage for acid-related dyspepsia
  • Dosage for prophylaxis of acid aspiration
  • Dosage for Zollinger-Ellison syndrome
  • Dosage for Helicobacter pylori eradication regimen in peptic ulcer disease
  • Pediatric use in severe ulcerating reflux esophagitis
  • Dosage for IV injection

Administration

  • Direction for use of IV Injection
  • Direction for use of IV Infusion
  • Instructions for reconstitution and administration
  • Use of freshly prepared solution
  • Maximum administration rate
  • Limited time for use after reconstitution

Interaction

  • Impact on absorption of ketoconazole
  • Metabolism through cytochrome P450
  • Potential delay in elimination of diazepam, phenytoin, and warfarin
  • Monitoring of patients receiving warfarin or phenytoin
  • Impact on blood concentration of phenytoin and coagulation time with warfarin
  • Plasma concentrations during concomitant administration
  • No evidence of interaction with certain drugs
  • Impact on the bioavailability of digoxin

Contraindications

  • Known hypersensitivity
  • Possibility of malignancy in gastric ulcer

Side Effects

  • Skin rash, urticaria, and pruritus
  • Photosensitivity, bullous eruption, and erythema multiforme
  • Diarrhea and headache
  • Gastrointestinal reactions
  • Dry mouth, stomatitis, and candidiasis
  • Paraesthesia
  • Dizziness, light headedness, and feeling faint
  • Mental confusion, agitation, and depression
  • Arthritic and myalgic symptoms
  • Reported cases of blurred vision, taste disturbance, and peripheral edema
  • Hepatic and hematologic reactions

Pregnancy & Lactation

  • No adverse effects on pregnancy or health of the fetus/newborn child
  • Usage recommendation during pregnancy
  • No information available on passage into breast milk
  • Recommendation to discontinue breastfeeding if essential use

Precautions & Warnings

  • Avoid concomitant use of clopidogrel
  • Possible association with increased risk for osteoporosis-related fractures
  • Occasional observation of atrophic gastritis in long-term use
  • Potential for methotrexate toxicities with concomitant use

Therapeutic Class

Proton Pump Inhibitor

Storage Conditions

Dry place away from light and heat, keep out of reach of children

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