Omegut 20 mg (Capsule (Enteric Coated))

Unit Price: ৳ 5.00 (10 x 10: ৳ 500.00)
Strip Price: ৳ 50.00

Medicine Details

Category Details
Generic Omeprazole
Company Popular pharmaceuticals ltd
Also available as
Omegut 40 mg capsule Omegut 40 mg injection

Indications

  • Treatment of gastric and duodenal ulcer
  • NSAID-associated duodenal and gastric ulcer treatment
  • Prophylaxis in patients with a history of NSAID-associated duodenal and gastric ulcer
  • Gastro-esophageal reflux disease treatment
  • Long-term management of acid reflux disease
  • Acid-related dyspepsia treatment
  • Severe ulcerating reflux esophagitis treatment
  • Prophylaxis of acid aspiration during general anesthesia
  • Treatment of Zollinger-Ellison syndrome
  • Treatment of Helicobacter pylori-induced peptic ulcer

Pharmacology

  • Omeprazole as an inhibitor of gastric acid secretion
  • Inhibition of gastric acid secretion by blocking H+/K+ ATPase enzyme
  • Onset of the antisecretory effect within one hour
  • Maximum effect occurring within two hours
  • Inhibition of secretion lasting up to 72 hours
  • Gradual return of secretory activity over 3 to 5 days

Dosage

  • Daily dosage for benign gastric and duodenal ulcer
  • NSAID-associated duodenal or gastric ulcer dosage
  • Dosage for gastro-esophageal reflux disease
  • Long-term management of acid reflux disease dosage
  • Dosage for acid-related dyspepsia
  • Dosage for prophylaxis of acid aspiration
  • Dosage for Zollinger-Ellison syndrome
  • Helicobacter pylori eradication regimen dosage
  • Pediatric dosage for severe ulcerating reflux esophagitis
  • IV Injection dosage for prophylaxis of acid aspiration
  • IV Injection dosage for duodenal ulcer, gastric ulcer, or reflux esophagitis
  • IV Injection dosage for Zollinger-Ellison syndrome

Administration

  • Direction for use of IV Injection
  • Direction for use of IV Infusion
  • Instruction for reconstitution of IV injection solution
  • Instruction for reconstitution of IV infusion solution

Interaction

  • Impact on absorption of ketoconazole
  • Metabolism through cytochrome P450 affecting diazepam, phenytoin, and warfarin
  • Monitoring and potential dose adjustment for patients on warfarin or phenytoin
  • Interaction with clarithromycin during H. pylori eradication
  • No evidence of interaction with phenacetin, theophylline, caffeine, and more

Contraindications

  • Hypersensitivity to omeprazole
  • Exclusion of malignancy before treatment

Side Effects

  • Mild and reversible adverse reactions
  • Reported skin rash, urticaria, and pruritus
  • Isolated cases of photosensitivity, bullous eruption, and more

Pregnancy & Lactation

  • Adverse effects during pregnancy not indicated
  • Limited information on passage into breast milk
  • Discontinuation of breastfeeding if essential

Precautions & Warnings

  • Avoid concomitant use of clopidogrel and omeprazole
  • Possible association with increased risk for osteoporosis-related fractures
  • Not established for pediatric patients less than 18 years of age

Therapeutic Class

  • Proton Pump Inhibitor

Storage Conditions

  • Keep in a dry place away from light and heat

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