Omirex 40 mg (Capsule (Enteric Coated))

Unit Price: ৳ 8.02 (5 x 4: ৳ 160.40)

Strip Price: ৳ 32.08

Medicine Details

Gastric and duodenal ulcer
NSAID-associated duodenal and gastric ulcer
Prophylaxis in patients with a history of NSAID-associated duodenal and gastric ulcer
Gastro-esophageal reflux disease
Long-term management of acid reflux disease
Acid-related dyspepsia
Severe ulcerating reflux esophagitis
Prophylaxis of acid aspiration during general anesthesia
Zollinger-Ellison syndrome
Helicobacter pylori-induced peptic ulcer

20 mg once daily for benign gastric and duodenal ulcer
40 mg daily for severe or recurrent cases of ulcer
10-20 mg daily for prevention of relapse in duodenal ulcer
20 mg once daily for 4-8 weeks for Gastro-esophageal reflux disease
10-20 mg daily for long-term management of acid reflux disease
40 mg on the preceding evening and 2-6 hours before surgery for prophylaxis of acid aspiration
Initially 60 mg once daily for Zollinger-Ellison syndrome
20 mg twice daily in association with antimicrobial agents for Helicobacter pylori eradication
10-40 mg once daily for 4-12 weeks in pediatric use for severe ulcerating reflux esophagitis

Omeprazole IV injection for intravenous administration only
IV injection given slowly over a period of 5 minutes
IV infusion given over a period of 20-30 minutes or more
Reconstituted solution used within 4 hours for IV injection and 12 hours for IV infusion
Solution not mixed or co-administered in the same infusion set with any other drug

Decreased intragastric acidity may reduce absorption of ketoconazole during treatment
Metabolized in the liver through cytochrome P450
Can delay the elimination of diazepam, phenytoin and warfarin
Plasma concentrations of Omeprazole and clarithromycin are increased during concomitant administration
No evidence of interaction with phenacetin, theophylline, caffeine, propranolol, metoprolol, cyclosporin, lidocaine, quinidine, estradiol, amoxycillin or antacids
No evidence of interaction with piroxicam, diclofenac or naproxen
Simultaneous treatment with Omeprazole and digoxin in healthy subjects lead to a 10% increase in the bioavailability of digoxin

Known hypersensitivity to Omeprazole
Presence of suspected gastric ulcer without excluding the possibility of malignancy

Skin rash, urticaria, and pruritus
Photosensitivity, bullous eruption, and erythema multiforme in isolated cases
Diarrhoea and headache, severe enough to require discontinuation of therapy in a small number of patients
Constipation, nausea/vomiting, flatulence, and abdominal pain
Dry mouth, stomatitis, and candidiasis in isolated cases
Paraesthesia
Dizziness, light-headedness, and faint feeling
Somnolence, insomnia, and vertigo
Reversible mental confusion, agitation, depression, and hallucinations in severely ill patients
Arthritic and myalgic symptoms, resolved when therapy is stopped
Blurred vision, taste disturbance, peripheral oedema, increased sweating, gynaecomastia, and more

No adverse effects of Omeprazole on pregnancy or on the health of the fetus/newborn child
Omeprazole can be used during pregnancy
No information available on the passage of Omeprazole into breast milk or its effects on the neonate
Breast-feeding should be discontinued if the use of Omeprazole is considered essential
Safety and effectiveness not established in pediatric patients less than 18 years of age

Avoid concomitant use of clopidogrel and Omeprazole
Observational studies suggest an increased risk for osteoporosis-related fractures with PPI therapy