Prevas 40 mg (Capsule (Enteric Coated))

Unit Price: ৳ 8.00 (3 x 10: ৳ 240.00)

Strip Price: ৳ 80.00

Medicine Details

Category	Details
Generic	Omeprazole
Company	General pharmaceuticals ltd
Also available as	Prevas 20 mg capsule Prevas 40 mg injection

Treatment of gastric and duodenal ulcer
NSAID-associated duodenal and gastric ulcer
Prophylaxis in patients with a history of NSAID-associated duodenal and gastric ulcer
Gastro-esophageal reflux disease
Long-term management of acid reflux disease
Acid-related dyspepsia
Severe ulcerating reflux esophagitis
Prophylaxis of acid aspiration during general anesthesia
Zollinger-Ellison syndrome
Helicobacter pylori-induced peptic ulcer

20 mg once daily for benign gastric and duodenal ulcer
40 mg daily for severe or recurrent cases
10-20 mg daily for prevention of relapse in duodenal ulcer
20 mg once daily for NSAID-associated duodenal or gastric ulcer
20 mg once daily for 4-8 weeks for gastro-esophageal reflux disease
40 mg once daily for 8 weeks in refractory gastro-esophageal reflux disease
10-20 mg daily for long-term management of acid reflux disease
10-20 mg once daily for 2-4 weeks for acid-related dyspepsia
40 mg for prophylaxis of acid aspiration during general anesthesia
60 mg once daily for Zollinger-Ellison syndrome
Amoxicillin 500 mg and Metronidazole 400 mg both three times a day for one week for Helicobacter pylori-induced peptic ulcer
Clarithromycin 250 mg and Metronidazole 400 mg both twice a day for one week for Helicobacter pylori-induced peptic ulcer

For intravenous administration only
IV injection given slowly over a period of 5 minutes
IV infusion given over a period of 20-30 minutes or more
Solution for IV injection to be used within 4 hours of reconstitution
Solution for IV infusion to be used within 12 hours when dissolved in saline and within 6 hours when dissolved in 5% Dextrose

Decreased intragastric acidity may reduce absorption of ketoconazole
Metabolised in the liver through cytochrome P450, may delay the elimination of diazepam, phenytoin, and warfarin
May increase plasma concentrations of clarithromycin
No evidence of interaction with phenacetin, theophylline, caffeine, propranolol, metoprolol, cyclosporin, lidocaine, quinidine, estradiol, amoxycillin, or antacids
Absorption not affected by alcohol or food
No evidence of interaction with piroxicam, diclofenac, or naproxen
May increase the bioavailability of digoxin
Monitoring and dose adjustment recommended for warfarin or phenytoin when given concomitantly

Known hypersensitivity to omeprazole
Suspicion of gastric ulcer should exclude the possibility of malignancy before treatment

Skin rash, urticaria, and pruritus
Photosensitivity, bullous eruption, erythema multiforme, angioedema, and alopecia
Diarrhoea and headache
Constipation, nausea/vomiting, flatulence, and abdominal pain
Dry mouth, stomatitis, and candidiasis
Paraesthesia, dizziness, light-headedness, and feeling faint
Somnolence, insomnia, and vertigo
Reversible mental confusion, agitation, depression, and hallucinations
Arthritic and myalgic symptoms
Blurred vision, taste disturbance, peripheral oedema, increased sweating, gynaecomastia, and hematologic disorders
Anaphylactic shock, malaise, fever, bronchospasm, encephalopathy, hepatitis, interstitial nephritis, and hepatic failure

No adverse effects on pregnancy or health of fetus/newborn child in epidemiological studies
Use during pregnancy considered safe
No information on passage into breast milk or effects on the neonate
Breastfeeding should be discontinued if essential

Avoid concomitant use with clopidogrel
PPI therapy may be associated with increased risk for osteoporosis-related fractures
Atrophic gastritis noted occasionally in gastric corpus biopsies from long-term treatment
Concomitant use with methotrexate may lead to methotrexate toxicities