Prolok 20 mg (Capsule (Enteric Coated))

Unit Price: ৳ 5.50 (10 x 10: ৳ 550.00)
Strip Price: ৳ 55.00

Medicine Details

Title

  • Prolok

Categories

  • Medicine
  • Gastrointestinal Health

Description

  • Omeprazole, a substituted benzimidazole, is an inhibitor of gastric acid secretion.

Dosage Usage

  • 20 mg once daily for 4 weeks in duodenal ulceration
  • 8 weeks in gastric ulceration
  • Severe or recurrent cases dose to be increased to 40 mg daily
  • Maintenance dose for recurrent duodenal ulcer, 20 mg once daily

Indications

  • Gastric and duodenal ulcer
  • NSAID-associated duodenal and gastric ulcer
  • Gastro-esophageal reflux disease
  • Long-term management of acid reflux disease
  • Acid-related dyspepsia
  • Severe ulcerating reflux esophagitis

Mode of Action

  • Inhibits gastric acid secretion by blocking H+/K+ ATPase enzyme system
  • Onset of the antisecretory effect occurs within one hour
  • Maximum effect occurring within two hours
  • Inhibition of secretion lasts up to 72 hours

Administration

  • IV injection for prophylaxis of acid aspiration
  • IV infusion given over a period of 20-30 minutes or more

Interaction

  • Decreased intragastric acidity may reduce the absorption of ketoconazole
  • Metabolised in the liver through cytochrome P450
  • Can delay the elimination of diazepam, phenytoin, and warfarin

Contraindications

  • Known hypersensitivity to Omeprazole

Side Effects

  • Skin rash, urticaria, and pruritus
  • Photosensitivity, bullous eruption, erythema multiforme, angioedema, and alopecia
  • Diarrhoea and headache
  • Gastrointestinal reactions including constipation, nausea/vomiting, flatulence, and abdominal pain

Pregnancy Lactation

  • Omeprazole can be used during pregnancy

Precautions Warnings

  • Avoid concomitant use of clopidogrel and Prolok

Therapeutic Class

  • Proton Pump Inhibitor

Storage Conditions

  • Keep in a dry place away from light and heat

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