Xelopes 40 mg (Capsule (Enteric Coated))

Unit Price: ৳ 7.02 (5 x 6: ৳ 210.60)
Strip Price: ৳ 42.12

Medicine Details

Category Details
Generic Omeprazole
Company Beacon pharmaceuticals plc
Also available as
Xelopes 20 mg capsule Xelopes 40 mg injection

Indications

  • Treatment of gastric and duodenal ulcer
  • NSAID-associated duodenal and gastric ulcer treatment
  • Prophylaxis for patients with a history of NSAID-associated duodenal and gastric ulcer
  • Gastro-esophageal reflux disease treatment
  • Long-term management of acid reflux disease
  • Treatment of acid-related dyspepsia
  • Severe ulcerating reflux esophagitis treatment
  • Prophylaxis of acid aspiration during general anesthesia
  • Zollinger-Ellison syndrome treatment
  • Helicobacter pylori-induced peptic ulcer treatment

Pharmacology

  • Inhibitor of gastric acid secretion
  • Blocks hydrogen-potassium-adenosine triphosphatase (H+/K+ ATPase) enzyme system
  • Onset of antisecretory effect within one hour
  • Maximum effect occurring within two hours
  • Inhibition of secretion lasts up to 72 hours
  • Gradual return of secretory activity over 3 to 5 days after discontinuation

Dosage

  • Oral and IV dosage instructions for different indications and conditions

Administration

  • Directions for use of IV Injection
  • Directions for use of IV Infusion

Interaction

  • Potential interactions with other medications metabolized by cytochrome P450
  • Monitoring and dose adjustment recommendations for concurrent use with warfarin or phenytoin
  • Increased plasma concentrations during concomitant administration with clarithromycin

Contraindications

  • Known hypersensitivity to omeprazole

Side Effects

  • Mild and reversible adverse reactions
  • Skin rash, urticaria, and pruritus reported
  • Photosensitivity, bullous eruption, erythema multiforme, angioedema, and alopecia reported
  • Diarrhoea, headache, constipation, nausea/vomiting, flatulence, and abdominal pain reported
  • Dry mouth, stomatitis, and candidiasis reported
  • Paraesthesia, dizziness, light headedness, and feeling faint associated with treatment
  • Somnolence, insomnia, and vertigo reported
  • Reversible mental confusion, agitation, depression, and hallucinations reported
  • Arthritic and myalgic symptoms reported

Pregnancy & Lactation

  • Results from epidemiological studies indicate no adverse effects on pregnancy or the fetus/newborn child
  • Consideration for use during pregnancy
  • No information available on passage into breast milk or effects on the neonate
  • Discontinuation of breastfeeding if essential use is considered

Precautions & Warnings

  • Avoid concomitant use of clopidogrel
  • Association with increased risk for osteoporosis-related fractures
  • Atrophic gastritis noted occasionally in long-term treatment
  • Potential for methotrexate toxicities with concomitant use of PPIs

Therapeutic Class

  • Proton Pump Inhibitor

Storage Conditions

  • Keep in a dry place away from light and heat
  • Keep out of the reach of children

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