Asector 20 mg (Capsule (Enteric Coated))
Unit Price: ৳ 7.02 (6 x 10: ৳ 421.00)
Strip Price: ৳ 70.17
Medicine Details
| Category | Details |
|---|---|
| Generic | Esomeprazole |
| Company | Novo healthcare and pharma ltd |
| Also available as |
Title
- Asector 20 mg Capsule
Categories
- Medicine
- Proton Pump Inhibitor
- Gastrointestinal
Indications
- Relieves chronic heartburn symptoms
- Heals erosive esophagitis
- Maintains healing of erosive esophagitis
- Eradicates Helicobacter pylori infection
- Treats Zollinger-Ellison Syndrome
- Manages acid-related Dyspepsia
- Treats Duodenal & Gastric ulcer
Mode of Action
- Acts as a proton pump inhibitor
- Suppresses gastric acid secretion
- Specifically inhibits H+/K+-ATPase
- Provides better acid control than racemic proton pump inhibitors
- Exhibits peak plasma levels at approximately 1.5 hours after oral administration
- Extensively metabolized in the liver by cytochrome P450 (CYP) enzyme system
- Plasma elimination half-life is approximately 1–1.5 hours
- Increases plasma levels when administered in combination with certain antimicrobials
Dosage
- 20 mg or 40 mg Once Daily for 4-8 Weeks for healing erosive esophagitis
- 20 mg Once Daily for maintenance of healing of erosive esophagitis
- 20 mg Once Daily for symptomatic GERD
- Triple Therapy for Helicobacter pylori eradication
- Dose of 20-80 mg once daily for Zollinger-Ellison Syndrome
- 20-40 mg once daily for acid-related Dyspepsia
- 20 mg once daily for 2-4 weeks for Duodenal ulcer
- 20-40 mg once daily for 4-8 weeks for Gastric ulcer
- Dosage adjustments for pediatric and adult patients for intravenous administration
- 80 mg IV infusion for adults to reduce the risk of rebleeding of Gastric or Duodenal Ulcers following therapeutic endoscopy
Administration
- Tablet or capsule should be swallowed whole and taken one hour before a meal
- Oral suspension can be administered with water and via nasogastric or gastric tube
- IV injection must be administered intravenously over a period of at least 3 minutes
- Precautions to be taken for oral administration in specific patient population
Interaction
- Extensively metabolized by CYP2C19 and CYP3A4
- Unlikely to inhibit several CYP enzymes
- May potentially interfere with the absorption of specific drugs
- No clinically significant interactions with certain medications
Contraindications
- Contraindicated in patients with known hypersensitivity to any of the formulation
Side Effects
- Headache
- Diarrhoea
- Nausea
- Flatulence
- Abdominal pain
- Constipation
- Dry mouth
Pregnancy & Lactation
- No adequate and well-controlled studies in pregnant women
- No adverse effects on pregnant or breastfeeding women reported
- Excretion in milk not studied
- Breastfeeding may be discontinued if essential
Precautions & Warnings
- Symptomatic response does not preclude presence of gastric malignancy
- Specific instructions for patients with difficulty swallowing capsules
- Use of antacids concurrently
Use in Special Populations
- Safety and effectiveness in pediatric patients not established
- No overall differences in safety and efficacy observed in elderly patients
- No dosage adjustment recommended for patients with specific conditions
Overdose Effects
- Lethal dose observed in animal studies
- No reports of overdose in humans
- No specific antidote known
- Treatment should be symptomatic and supportive
- Consideration of multiple drug ingestion
Storage Conditions
- Store at a temperature not exceeding 30°C in a dry place
- Protect from light and moisture
- Keep out of reach of children
Chemical Structure
- Molecular Formula: C17H19N3O3S
- Chemical Structure available
Commonly Asked Questions
- Provides an understanding of Asector 20 mg Capsule's usage
- Describes its side effects and precautions
- Quick tips for usage and essential precautions