Emep 20 mg (Tablet (Enteric Coated))
Unit Price: ৳ 7.00 (6 x 10: ৳ 420.00)
Strip Price: ৳ 70.00
Medicine Details
Category | Details |
---|---|
Generic | Esomeprazole |
Company | Aristopharma ltd |
Also available as |
Indications
- Relief from chronic heartburn symptoms
- Healing of erosive esophagitis
- Maintenance of healing of erosive esophagitis
- Eradication of Helicobacter pylori infection
- Treatment of Zollinger-Ellison Syndrome
- Acid related Dyspepsia
- Treatment of duodenal and gastric ulcers
Pharmacology
- Proton pump inhibitor
- Suppression of gastric acid secretion
- Specific inhibition of the H+/K+-ATPase
- Enteric-coated pellet formulation
- Metabolized in the liver by CYP enzymes
- Plasma protein binding
- Extensively metabolized in the liver
- Plasma elimination half-life
- Combination therapy with antimicrobials
- Pharmacokinetic parameters for combination therapy
Dosage
- 20 mg or 40 mg once daily for healing of erosive esophagitis
- 20 mg once daily for maintenance of healing of erosive esophagitis
- 20 mg once daily for symptomatic GERD
- Triple therapy dosage for Helicobacter pylori eradication
- 20-80 mg once daily for Zollinger-Ellison Syndrome
- 20-40 mg once daily for acid-related dyspepsia
- 20 mg once daily for duodenal ulcer
- 20-40 mg once daily for gastric ulcer
Administration
- Tablet or capsule should be swallowed whole and taken one hour before a meal
- Preparation and administration of oral suspension
- IV Injection preparation and administration
Interaction
- Metabolized in the liver by CYP2C19 and CYP3A4
- Inhibition of gastric acid secretion and drug absorption
- Co-administration with clarithromycin
- Absence of clinically significant interactions with certain drugs
Contraindications
- Known hypersensitivity to any of the formulation
Side Effects
- Headache
- Diarrhoea
- Nausea
- Flatulence
- Abdominal pain
- Constipation
- Dry mouth
Pregnancy & Lactation
- No adequate and well-controlled studies in pregnant women
- No teratogenic effects observed in animal studies
- Excretion of esomeprazole in milk not studied
- Discontinuation of breastfeeding if essential use of esomeprazole
Precautions & Warnings
- Symptomatic response to therapy does not preclude the presence of gastric malignancy
- Administration one hour before meals
- Use with antacids
- Instructions for patients
Use in Special Populations
- Safety and effectiveness in paediatric patients not established
- No overall differences in safety and efficacy in geriatric patients
- No dosage adjustment for mild to moderate hepatic insufficiency
- Pharmacokinetics not expected to be altered in renal impairment
Overdose Effects
- Lethal dose in rats
- Signs of acute toxicity
- No specific antidote
- Symptomatic and supportive treatment
Storage Conditions
- Temperature and moisture conditions for storage
Chemical Structure
- Molecular formula
- Chemical structure image
Common Questions about Emep 20 mg Tablet
- Uses of Emep 20 mg Tablet
- Side effects of Emep 20 mg Tablet
- Safety during pregnancy and breastfeeding
- Time to start of action
- Quick tips for usage