Emep 20 mg (Capsule (Enteric Coated))

Unit Price: ৳ 8.00 (6 x 10: ৳ 480.00)
Strip Price: ৳ 80.00

Medicine Details

Category Details
Generic Esomeprazole
Company Aristopharma ltd
Also available as
Emep 20 mg tablet Emep 40 mg capsule Emep 40 mg injection

Indications

  • Relief from chronic heartburn symptoms
  • Healing of erosive esophagitis
  • Maintenance of healing of erosive esophagitis
  • Eradication of Helicobacter pylori infection in patients with duodenal ulcer disease
  • Zollinger-Ellison Syndrome treatment
  • Treatment of acid-related Dyspepsia
  • Treatment of Duodenal & Gastric ulcer

Pharmacology

  • Proton pump inhibitor
  • Suppresses gastric acid secretion
  • Specific inhibition of the H+/K+-ATPase
  • First single optical isomer of proton pump inhibitor
  • Enteric-coated pellet formulation
  • Peak plasma levels occur at approximately 1.5 hours
  • Extensively metabolized in the liver
  • Plasma elimination half-life of approximately 1–1.5 hours

Dosage

  • Oral dosage form for various conditions
  • IV Injection or IV infusion for GERD with Erosive Esophagitis
  • Different dosages for pediatric patients based on body weight
  • Special dosage for risk reduction of rebleeding of Gastric or Duodenal Ulcers following therapeutic endoscopy in adults

Administration

  • Tablet or capsule should be swallowed whole and taken one hour before a meal
  • Oral Suspension administration instructions
  • IV Injection preparation and administration

Interaction

  • Metabolized by CYP2C19 and CYP3A4
  • Not likely to inhibit certain CYP enzymes
  • Potential interference with CYP2C19
  • May interfere with the absorption of drugs where gastric pH is important
  • No clinically significant interactions with specified drugs

Contraindications

  • Hypersensitivity to any of the formulation

Side Effects

  • Headache
  • Diarrhea
  • Nausea
  • Flatulence
  • Abdominal pain
  • Constipation
  • Dry mouth

Pregnancy & Lactation

  • No adequate and well-controlled studies in pregnant women
  • No teratogenic effects in animal studies
  • Excretion of esomeprazole in milk not studied
  • Breastfeeding should be discontinued if the use of esomeprazole is considered essential

Precautions & Warnings

  • Symptomatic response to therapy does not preclude the presence of gastric malignancy
  • Specific instructions for patients with difficulty swallowing capsules
  • Usage of antacids while taking the medicine

Use in Special Populations

  • Safety and effectiveness in pediatric patients not established
  • No overall differences in safety and efficacy observed between the elderly and younger individuals
  • No dosage adjustment recommended for patients with mild to moderate hepatic insufficiency
  • Pharmacokinetics not expected to be altered in patients with renal impairment

Overdose Effects

  • Lethal effects observed in rats at high doses
  • Symptomatic and supportive treatment recommended in case of overdose

Storage Conditions

  • Store at a temperature not exceeding 30°C
  • Protect from light and moisture
  • Keep out of reach of children

Chemical Structure

  • Molecular Formula: C17H19N3O3S

Common Questions about Emep 20 mg Capsule

  • Description of Emep 20 mg Capsule
  • Multiple uses of Emep 20 mg Capsule
  • Common side effects of Emep 20 mg Capsule
  • Recommendation for pregnant or breastfeeding women
  • Duration for Emep 20 mg Capsule to work
  • Quick tips for taking Emep 20 mg Capsule

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