Emep 40 mg (Capsule (Enteric Coated))
Unit Price: ৳ 11.00 (4 x 10: ৳ 440.00)
Strip Price: ৳ 110.00
Medicine Details
Category | Details |
---|---|
Generic | Esomeprazole |
Company | Aristopharma ltd |
Also available as |
Indications
- Relief from chronic heartburn symptoms
- Healing of erosive esophagitis
- Maintenance of healing of erosive esophagitis
- Eradication of Helicobacter pylori infection
- Treatment of Zollinger-Ellison Syndrome
- Relief from acid-related dyspepsia
- Treatment of duodenal and gastric ulcers
Pharmacology
- Suppresses gastric acid secretion
- Specific inhibition of the H+/K+-ATPase in the gastric parietal cell
- Provides better acid control than racemic proton pump inhibitors
- Peak plasma levels occur at approximately 1.5 hours after oral administration
- Extensively metabolized in the liver
- Plasma elimination half-life is approximately 1–1.5 hours
Dosage
- Oral dosage form for various indications
- IV Injection and IV infusion for different patient groups
Administration
- Tablet or capsule should be swallowed whole and taken one hour before a meal
- Oral Suspension administration instructions
- IV Injection preparation and administration
Interactions
- Metabolized by CYP2C19 and CYP3A4
- No clinically relevant interactions with certain drugs
Contraindications
- Contraindicated in patients with known hypersensitivity to any of the formulation
Side Effects
- Frequently occurring adverse events include headache, diarrhea, nausea, flatulence, abdominal pain, constipation, and dry mouth
Pregnancy & Lactation
- No adequate and well-controlled studies in pregnant women
- No teratogenic effects observed in animal studies
- The excretion of esomeprazole in milk has not been studied
Precautions & Warnings
- Symptomatic response does not preclude the presence of gastric malignancy
- Administration recommendations for patients with difficulty swallowing capsules
Use in Special Populations
- Safety and effectiveness not established in pediatric patients
- No overall differences in safety and efficacy observed between the elderly and younger individuals
- No dosage adjustment recommended for patients with mild to moderate hepatic insufficiency
- Pharmacokinetics in patients with renal impairment not expected to be altered
Overdose Effects
- Signs of acute toxicity observed in animal studies
- No reports of overdose with esomeprazole
- No specific antidote known
Storage Conditions
- Store at a temperature not exceeding 30°C in a dry place
- Protect from light and moisture
- Keep out of reach of children
Chemical Structure
- Molecular Formula: C17H19N3O3S
- Chemical Structure Image available
Common Questions
- Multiple uses of Emep 40 mg Capsule
- Common side effects of Emep 40 mg Capsule
- Recommendation for pregnant or breastfeeding individuals
- Onset of action for Emep 40 mg Capsule
- Quick tips for using Emep 40 mg Capsule
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