Emep 40 mg (Capsule (Enteric Coated))

Unit Price: ৳ 11.00 (4 x 10: ৳ 440.00)
Strip Price: ৳ 110.00

Medicine Details

Indications

  • Relief from chronic heartburn symptoms
  • Healing of erosive esophagitis
  • Maintenance of healing of erosive esophagitis
  • Eradication of Helicobacter pylori infection
  • Treatment of Zollinger-Ellison Syndrome
  • Relief from acid-related dyspepsia
  • Treatment of duodenal and gastric ulcers

Pharmacology

  • Suppresses gastric acid secretion
  • Specific inhibition of the H+/K+-ATPase in the gastric parietal cell
  • Provides better acid control than racemic proton pump inhibitors
  • Peak plasma levels occur at approximately 1.5 hours after oral administration
  • Extensively metabolized in the liver
  • Plasma elimination half-life is approximately 1–1.5 hours

Dosage

  • Oral dosage form for various indications
  • IV Injection and IV infusion for different patient groups

Administration

  • Tablet or capsule should be swallowed whole and taken one hour before a meal
  • Oral Suspension administration instructions
  • IV Injection preparation and administration

Interactions

  • Metabolized by CYP2C19 and CYP3A4
  • No clinically relevant interactions with certain drugs

Contraindications

  • Contraindicated in patients with known hypersensitivity to any of the formulation

Side Effects

  • Frequently occurring adverse events include headache, diarrhea, nausea, flatulence, abdominal pain, constipation, and dry mouth

Pregnancy & Lactation

  • No adequate and well-controlled studies in pregnant women
  • No teratogenic effects observed in animal studies
  • The excretion of esomeprazole in milk has not been studied

Precautions & Warnings

  • Symptomatic response does not preclude the presence of gastric malignancy
  • Administration recommendations for patients with difficulty swallowing capsules

Use in Special Populations

  • Safety and effectiveness not established in pediatric patients
  • No overall differences in safety and efficacy observed between the elderly and younger individuals
  • No dosage adjustment recommended for patients with mild to moderate hepatic insufficiency
  • Pharmacokinetics in patients with renal impairment not expected to be altered

Overdose Effects

  • Signs of acute toxicity observed in animal studies
  • No reports of overdose with esomeprazole
  • No specific antidote known

Storage Conditions

  • Store at a temperature not exceeding 30°C in a dry place
  • Protect from light and moisture
  • Keep out of reach of children

Chemical Structure

  • Molecular Formula: C17H19N3O3S
  • Chemical Structure Image available

Common Questions

  • Multiple uses of Emep 40 mg Capsule
  • Common side effects of Emep 40 mg Capsule
  • Recommendation for pregnant or breastfeeding individuals
  • Onset of action for Emep 40 mg Capsule
  • Quick tips for using Emep 40 mg Capsule

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