Eprazol 20 mg (Capsule (Enteric Coated))

Unit Price: ৳ 7.02 (10 x 10: ৳ 702.00)
Strip Price: ৳ 70.20

Medicine Details

Category Details
Generic Esomeprazole
Company Labaid pharma ltd
Also available as
Eprazol 40 mg capsule

Indications

  • Relief from chronic heartburn symptoms
  • Healing of erosive esophagitis
  • Maintenance of healing of erosive esophagitis
  • Eradication of Helicobacter pylori infection
  • Treatment of Zollinger-Ellison Syndrome
  • Treatment of acid related Dyspepsia
  • Treatment of Duodenal & Gastric ulcer

Pharmacology

  • Proton pump inhibitor
  • Specific inhibition of the H+/K+-ATPase
  • Better acid control than racemic proton pump inhibitors
  • Enteric-coated pellet formulation of esomeprazole magnesium
  • Peak plasma levels occur at approximately 1.5 hours
  • Extensively metabolized in the liver
  • Plasma elimination half-life of approximately 1-1.5 hours

Dosage

  • Oral dosage form available
  • Dosage ranges for different indications
  • IV Injection or IV infusion option
  • Different dosages for adult and pediatric patients

Administration

  • Tablet or capsule should be swallowed whole
  • Oral suspension instructions
  • IV Injection preparation and administration

Interaction

  • Extensively metabolized in the liver
  • No clinically relevant interactions with specific CYP enzymes expected
  • Potential interference with CYP2C19
  • Does not have significant interactions with specific drugs

Contraindications

  • Contraindicated in patients with known hypersensitivity

Side Effects

  • Frequently occurring adverse events
  • No significant difference in adverse events during maintenance treatment

Pregnancy & Lactation

  • No adequate and well-controlled studies in pregnant women
  • Animal studies show no teratogenic effects
  • Excretion of esomeprazole in milk not studied
  • Breast-feeding should be discontinued if essential

Precautions & Warnings

  • Symptomatic response does not preclude presence of gastric malignancy
  • Specific instructions for patients with difficulty swallowing capsules
  • Use of antacids while taking esomeprazole

Use in Special Populations

  • Safety and effectiveness not established in pediatric patients
  • No overall differences in safety and efficacy observed between elderly and younger individuals
  • No dosage adjustment recommended for patients with mild to moderate hepatic insufficiency
  • Pharmacokinetics in patients with renal impairment not expected to be altered

Overdose Effects

  • Signs of acute toxicity
  • No specific antidote known
  • Treatment should be symptomatic and supportive

Storage Conditions

  • Store at a temperature not exceeding 30°C
  • Protect from light and moisture
  • Keep out of reach of children

Chemical Structure

  • Molecular Formula: C17H19N3O3S

Common Questions about Eprazol 20 mg Capsule

  • PPI used to treat gastroesophageal reflux disease (GERD), ulcers, and other conditions
  • Common side effects
  • Suitability for pregnant or breastfeeding individuals
  • Typical onset of action
  • Quick tips for usage

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