Erazole 20 mg (Tablet (Enteric Coated))

Unit Price: ৳ 5.00 (3 x 10: ৳ 150.00)
Strip Price: ৳ 50.00

Medicine Details

Category Details
Generic Esomeprazole
Company Kemiko pharmaceuticals ltd
Also available as
Erazole 40 mg capsule Erazole 20 mg capsule Erazole 40 mg tablet

Title

Erazole 20 mg Tablet

Categories

  • Medicine
  • Gastroenterology
  • Proton Pump Inhibitor

Description

Erazole is a proton pump inhibitor used to relieve chronic heartburn symptoms, heal erosive esophagitis, eradicate Helicobacter pylori infection, treat Zollinger-Ellison Syndrome, acid-related dyspepsia, duodenal & gastric ulcers, and maintain healing of erosive esophagitis

Dimensions

  • TabletSize: 20 mg
  • Form:
    • Tablet
    • Capsule
    • Oral Suspension
    • IV Injection
    • IV Infusion

Color

White

Functions

  • ReliefFrom:
    • Chronic Heartburn Symptoms
    • GERD Symptoms
  • HealingOf:
    • Erosive Esophagitis
  • MaintenanceOfHealingOf:
    • Erosive Esophagitis
  • EradicationOf:
    • Helicobacter Pylori Infection
  • TreatmentOf:
    • Zollinger-Ellison Syndrome
    • Acid-related Dyspepsia
    • Duodenal & Gastric Ulcers

Dosage

  • Oral:
    • HealingOfErosiveEsophagitis:
      • 20 mg or 40 mg Once Daily for 4-8 Weeks
    • SymptomaticGERD: 20 mg Once Daily for 4 Weeks
    • MaintenanceOfHealingOfErosiveEsophagitis: 20 mg Once Daily
    • HelicobacterPyloriEradication: 40 mg Once Daily for 10 days
    • ZollingerEllisonSyndrome: 20-80 mg Once Daily
    • AcidRelatedDyspepsia: 20-40 mg Once Daily for 2-4 weeks
    • DuodenalUlcer: 20 mg Once Daily for 2-4 weeks
    • GastricUlcer: 20-40 mg Once Daily for 4-8 weeks
  • IV:
    • GerdWithErosiveEsophagitis: 20 mg or 40 mg Once Daily
    • InfusionTimeAdultPatients:
      • >3 Minutes
      • 10-30 minutes
    • PediatricPatients:
      • BodyWeightLt55Kg: 10 mg Once daily
      • BodyWeightGt55Kg: 20 mg Once daily
      • 1MonthToLt1Year: 0.5 mg/kg Once daily
    • RiskReductionOfRebleeding: 80 mg

Administration

  • TabletOrCapsule: Swallowed whole, taken 1 hour before a meal
  • OralSuspension: Stir well, taken with water within 30 minutes
  • IVInjection: Administered over a period of at least 3 minutes

Interaction

  • MetabolismInhibition: Potential interference with CYP2C19 and absorption of certain drugs due to gastric pH change
  • ClinicallySignificantInteractions:
    • Phenytoin
    • Warfarin
    • Quinidine
    • Clarithromycin
    • Amoxicillin

Contraindications

  • Known Hypersensitivity to Any of the Formulation

SideEffects

  • Headache
  • Diarrhoea
  • Nausea
  • Flatulence
  • Abdominal Pain
  • Constipation
  • Dry Mouth

PregnancyAndLactation

  • StudiesInPregnantWomen: None
  • TeratogenicEffectsInAnimalStudies: None
  • ExcretionInMilk: Not studied
  • RecommendationForBreastfeeding: Discontinue if essential

PrecautionsAndWarnings

  • SymptomaticResponse: Does not rule out the presence of gastric malignancy
  • AdministrationInstructions: Taken at least one hour before meals
  • AdditionalInformationForPatients: Swallowing difficulties addressed with applesauce mix, can be taken with antacids

SpecialPopulations

  • PaediatricUse: Safety and effectiveness not established
  • GeriatricUse: No overall differences in safety and efficacy observed
  • HepaticInsufficiency:
    • MildToModerate: No dosage adjustment recommended
    • Severe: Dose of 20 mg once daily should not be exceeded
  • RenalInsufficiency: Pharmacokinetics not expected to be altered

OverdoseEffects

Acute toxicity signs include reduced motor activity, respiratory changes, tremor, ataxia, and intermittent clonic convulsions; no specific antidote known; treatment should be symptomatic and supportive

StorageConditions

Store at a temperature not exceeding 30°C in a dry place, protect from light and moisture, keep out of reach of children

ChemicalStructure

  • MolecularFormula: C17H19N3O3S
  • StructureImage: https://medex.com.bd/storage/res/g-res-433-esomeprazole-chemical-structure-Tj2Jfp1VmPkRjNXznKqC.svg

CommonlyAskedQuestions

  • Uses:
    • Gastroesophageal Reflux Disease (GERD)
    • Ulcers
    • Conditions That Involve Excess Stomach Acid
  • SideEffects:
    • Headaches
    • Diarrhea
    • Nausea
    • Gas
    • Stomach Pain
    • Constipation
    • Dry Mouth
  • RecommendationForPregnancyAndBreastfeeding: Discuss risks and benefits with a doctor
  • OnsetOfAction: Typically starts within a few hours of taking it

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