Esogel 40 mg (Capsule (Enteric Coated))

Unit Price: ৳ 9.00 (5 x 10: ৳ 450.00)
Strip Price: ৳ 90.00

Medicine Details

Category Details
Generic Esomeprazole
Company Novatek pharmaceuticals ltd
Also available as
Esogel 20 mg capsule Esogel 40 mg injection Esogel 20 mg tablet Esogel 40 mg tablet

Indications

  • Relief from chronic heartburn symptoms
  • Healing of erosive esophagitis
  • Maintenance of healing of erosive esophagitis
  • Eradication of Helicobacter pylori infection
  • Treatment of Zollinger-Ellison Syndrome
  • Management of acid-related Dyspepsia
  • Management of Duodenal & Gastric ulcer

Pharmacology

  • Proton pump inhibitor
  • Suppresses gastric acid secretion
  • Specific inhibition of the H+/K+-ATPase
  • Better acid control than racemic proton pump inhibitors
  • Enteric-coated pellet formulation
  • Metabolized in the liver by the cytochrome P450 enzyme system
  • Extensively metabolized
  • Plasma elimination half-life of approximately 1-1.5 hours

Dosage

  • Oral dosage form
  • IV Injection or IV infusion
  • Specific dosages for healing of erosive esophagitis, symptomatic GERD, Helicobacter pylori eradication, Zollinger-Ellison Syndrome, acid-related Dyspepsia, and Duodenal & Gastric ulcer
  • Different dosages for adult and pediatric patients
  • IV Infusion for specific patient groups
  • Dosage for risk reduction of rebleeding of Gastric or Duodenal Ulcers

Administration

  • Tablet or capsule should be swallowed whole and taken one hour before a meal
  • Oral Suspension instructions
  • IV Injection preparation and administration

Interaction

  • Extensively metabolized in the liver by CYP2C19 and CYP3A4
  • Inhibition of gastric acid secretion may interfere with drug absorption
  • No clinically significant interactions with certain drugs

Contraindications

  • Contraindicated in patients with known hypersensitivity to any of the formulation

Side Effects

  • Common adverse events include headache, diarrhea, nausea, flatulence, abdominal pain, constipation, and dry mouth
  • No difference in types of related adverse events seen during maintenance treatment up to 12 months compared to short-term treatment

Pregnancy & Lactation

  • No adequate and well-controlled studies in pregnant women
  • Animal studies have revealed no teratogenic effects
  • Excretion in milk has not been studied
  • Breastfeeding should be discontinued if essential

Precautions & Warnings

  • Symptomatic response does not preclude the presence of gastric malignancy
  • Instructions for patients on capsule administration
  • Use of antacids while taking Esogel

Use in Special Populations

  • Safety and effectiveness not established in pediatric patients
  • No overall differences in safety and efficacy observed between the elderly and younger individuals
  • No dosage adjustment recommended for patients with mild to moderate hepatic insufficiency
  • Pharmacokinetics not expected to be altered in patients with renal impairment

Overdose Effects

  • Lethal effects observed in animal studies at high doses
  • No specific antidote known
  • Supportive and symptomatic treatment recommended

Storage Conditions

  • Store at a temperature not exceeding 30°C in a dry place
  • Protect from light and moisture
  • Keep out of reach of children

Chemical Structure

  • Molecular Formula: C17H19N3O3S
  • Chemical Structure: (Image of chemical structure)

Common Questions about Esogel 40 mg Capsule

  • Description of Esogel 40 mg Capsule
  • Usages and conditions treated
  • Common side effects
  • Pregnancy and breastfeeding considerations
  • Onset of action and quick tips for usage

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