Esolok 20 mg (Tablet (Enteric Coated))

Unit Price: ৳ 6.00 (10 x 10: ৳ 600.00)
Strip Price: ৳ 60.00

Medicine Details

Title

  • Esolok 20 mg Tablet

Categories

  • Medicine
  • Pharmaceutical

Description

  • Proton pump inhibitor for acid suppression
  • Treatment for GERD, erosive esophagitis, Duodenal ulcer, Gastric ulcer, Zollinger-Ellison Syndrome
  • Indicated for chronic heartburn symptoms
  • Pharmacology includes H+/K+-ATPase inhibition
  • Absorption peak at approximately 1.5 hours post oral administration
  • Metabolized by CYP2C19 and CYP3A4 enzymes
  • Excretion through urine and feces
  • Combination therapy with antimicrobials for H. pylori eradication
  • Dosage ranges for different indications
  • Oral and IV administration instructions
  • Contraindicated in hypersensitivity cases
  • Common side effects like headache, diarrhea, nausea, abdominal pain
  • No significant drug interactions with certain medications
  • Storage conditions at temperature below 30°C
  • No known specific antidote for overdose

Color Options

  • White

Dosage Form

  • Tablet
  • Oral Suspension
  • IV Injection

Dosage Strengths

  • 20 mg
  • 40 mg
  • 80 mg

Dosage Instructions

  • Taken orally one hour before meals
  • Oral suspension mixed with water
  • IV injection over 3 minutes
  • Pediatric dosages based on weight

Pharmacokinetics

  • Steady state AUC and Cmax increased during triple combination therapy
  • Volume of distribution at steady state is approximately 16 L
  • Plasma protein binding constant at 97%
  • Systemic bioavailability approximately 90% after repeated dosing

Special Populations

  • Safety and effectiveness not established in pediatric patients
  • No dosage adjustment in mild to moderate hepatic insufficiency
  • Renal impairment not expected to alter pharmacokinetics
  • No overall differences in safety observed in geriatric patients

Pregnancy & Lactation

  • No well-controlled studies in pregnant women
  • No teratogenic effects observed in animal studies
  • Breastfeeding should be discontinued if essential

Precautions & Warnings

  • Symptomatic response does not rule out gastric malignancy
  • Capsules should be taken at least one hour before meals
  • Antacids may be used concurrently

Chemical Structure

  • C17H19N3O3S

Common Questions

  • Uses of Esolok 20 mg Tablet
  • Side effects of Esolok 20 mg Tablet
  • Interactions with other drugs
  • Dosage instructions for pediatric patients
  • Storage conditions for Esolok 20 mg Tablet

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