Esoral 40 mg/vial (IV Injection)

40 mg vial: ৳ 90.00

Medicine Details

Title

  • Esoral 40 mg/vial Injection

Categories

  • Medicine
  • Health & Wellness
  • Gastrointestinal Health

Description

  • A proton pump inhibitor (PPI) used to treat gastroesophageal reflux disease (GERD), ulcers, and conditions involving excessive stomach acid production.
  • Reduces chronic heartburn symptoms and other symptoms associated with GERD.
  • Heals erosive esophagitis and maintains its healing.
  • Eradicates Helicobacter pylori infection in patients with duodenal ulcer disease when used in combination with amoxicillin and clarithromycin.
  • Used for Zollinger-Ellison Syndrome, acid-related dyspepsia, duodenal & gastric ulcers.

Dimensions

  • Vial size: 40 mg

Color options

  • Colorless

Functions

  • Reduces gastric acid secretion by inhibiting the H+/K+-ATPase in the gastric parietal cell.
  • Promotes better acid control than racemic proton pump inhibitors.
  • Supplies enteric-coated pellet formulation of esomeprazole magnesium for oral administration.

Materials

  • Esomeprazole magnesium
  • Sodium Chloride

Technical specifications

  • Absorption: Peak plasma levels occur at approximately 1.5 hours after oral administration.
  • Distribution: 97% bound to plasma proteins.
  • Metabolism: Extensively metabolized in the liver by the cytochrome P450 (CYP) enzyme system.
  • Excretion: Plasma elimination half-life is approximately 1-1.5 hours.
  • Steady state bioavailability is approximately 90% compared to 64% after a single dose.

Design elements

  • Enteric-coated pellets for oral dosage form.
  • Solution for injection prepared using 0.9% Sodium Chloride for intravenous injection.
  • Reconstituted solution for injection is clear and colorless to very slightly yellow.

Usability features

  • Oral dosage form should be swallowed whole and taken one hour before a meal.
  • Oral suspension should be stirred well and drunk within 30 minutes. Can be administered through a nasogastric or gastric tube.
  • IV Injection must be administered intravenously over a period of at least 3 minutes.

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