Esoral 40 mg/vial (IV Injection)
40 mg vial: ৳ 90.00
Medicine Details
Category | Details |
---|---|
Generic | Esomeprazole |
Company | Eskayef pharmaceuticals ltd |
Also available as |
Title
- Esoral 40 mg/vial Injection
Categories
- Medicine
- Health & Wellness
- Gastrointestinal Health
Description
- A proton pump inhibitor (PPI) used to treat gastroesophageal reflux disease (GERD), ulcers, and conditions involving excessive stomach acid production.
- Reduces chronic heartburn symptoms and other symptoms associated with GERD.
- Heals erosive esophagitis and maintains its healing.
- Eradicates Helicobacter pylori infection in patients with duodenal ulcer disease when used in combination with amoxicillin and clarithromycin.
- Used for Zollinger-Ellison Syndrome, acid-related dyspepsia, duodenal & gastric ulcers.
Dimensions
- Vial size: 40 mg
Color options
- Colorless
Functions
- Reduces gastric acid secretion by inhibiting the H+/K+-ATPase in the gastric parietal cell.
- Promotes better acid control than racemic proton pump inhibitors.
- Supplies enteric-coated pellet formulation of esomeprazole magnesium for oral administration.
Materials
- Esomeprazole magnesium
- Sodium Chloride
Technical specifications
- Absorption: Peak plasma levels occur at approximately 1.5 hours after oral administration.
- Distribution: 97% bound to plasma proteins.
- Metabolism: Extensively metabolized in the liver by the cytochrome P450 (CYP) enzyme system.
- Excretion: Plasma elimination half-life is approximately 1-1.5 hours.
- Steady state bioavailability is approximately 90% compared to 64% after a single dose.
Design elements
- Enteric-coated pellets for oral dosage form.
- Solution for injection prepared using 0.9% Sodium Chloride for intravenous injection.
- Reconstituted solution for injection is clear and colorless to very slightly yellow.
Usability features
- Oral dosage form should be swallowed whole and taken one hour before a meal.
- Oral suspension should be stirred well and drunk within 30 minutes. Can be administered through a nasogastric or gastric tube.
- IV Injection must be administered intravenously over a period of at least 3 minutes.
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