Esotid 20 mg (Capsule (Enteric Coated))

Unit Price: ৳ 7.00 (9 x 10: ৳ 630.00)
Strip Price: ৳ 70.00

Medicine Details

Category Details
Generic Esomeprazole
Company Opsonin pharma ltd
Also available as
Esotid 20 mg tablet Esotid 40 mg tablet Esotid 40 mg capsule Esotid 40 mg injection

Indications

  • Relief from chronic heartburn symptoms and other symptoms associated with GERD
  • Healing of erosive esophagitis
  • Maintenance of healing of erosive esophagitis
  • Eradication of Helicobacter pylori infection in patients with duodenal ulcer disease
  • Zollinger-Ellison Syndrome
  • Acid related Dyspepsia
  • Duodenal & Gastric ulcer

Pharmacology

  • Proton pump inhibitor
  • Suppression of gastric acid secretion
  • Inhibition of the H+/K+-ATPase in the gastric parietal cell
  • Better acid control than racemic proton pump inhibitors
  • Enteric-coated pellet formulation
  • Peak plasma levels occur at approximately 1.5 hours
  • Metabolized in the liver by the cytochrome P450 (CYP) enzyme system
  • Low plasma protein binding
  • Extensive metabolism
  • Plasma elimination half-life is approximately 1-1.5 hours

Dosage

  • Oral dosage form
  • IV Injection or IV infusion for GERD with Erosive Esophagitis
  • Different dosages for different indications
  • Dosage adjustments for pediatric and adult patients
  • Duration of treatment for different conditions

Administration

  • Tablet or capsule should be swallowed whole and taken one hour before a meal
  • Instructions for oral suspension administration
  • Instructions for IV Injection administration

Interaction

  • Extensively metabolized in the liver by CYP2C19 and CYP3A4
  • Not likely to inhibit CYPs 1A2, 2A6, 2C9, 2D6, 2E1 and 3A4
  • Potential interference with absorption of certain drugs
  • No clinically significant interactions with specific drugs

Contraindications

  • Known hypersensitivity to any of the formulation

Side Effects

  • Headache
  • Diarrhea
  • Nausea
  • Flatulence
  • Abdominal pain
  • Constipation
  • Dry mouth
  • No difference in types of related adverse events seen during maintenance treatment

Pregnancy & Lactation

  • No adequate and well-controlled studies in pregnant women
  • Animal studies have revealed no teratogenic effects
  • Breast-feeding should be discontinued if the use of esomeprazole is considered essential

Precautions & Warnings

  • Symptomatic response to therapy with Esotid does not preclude the presence of gastric malignancy
  • Instructions for patients
  • Use in Special Populations
  • Pediatric Use
  • Geriatric Use
  • Hepatic Insufficiency
  • Renal Insufficiency

Overdose Effects

  • Acute toxicity signs
  • No specific antidote known
  • Symptomatic and supportive treatment recommended

Storage Conditions

  • Store at a temperature not exceeding 30°C in a dry place
  • Protect from light and moisture
  • Keep out of reach of children

Chemical Structure

  • Molecular Formula: C17H19N3O3S
  • Chemical Structure Image

Common Questions

  • What is Esotid 20 mg Capsule?
  • What is Esotid 20 mg Capsule used for?
  • Side effects of Esotid 20 mg Capsule
  • Use during pregnancy or breastfeeding
  • Duration for Esotid 20 mg Capsule to work
  • Quick Tips

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