Esotid 40 mg (Capsule (Enteric Coated))

Title

• Esotid 40 mg Capsule

Categories

• Medicine
• Healthcare
• Pharmacy

Description

• Esotid 40 mg Capsule is a proton pump inhibitor (PPI) that works by reducing the amount of acid produced in the stomach. It is used to treat conditions such as gastroesophageal reflux disease (GERD), ulcers, and erosive esophagitis.

Indications

• Relief from chronic heartburn symptoms and other symptoms associated with GERD
• Healing of erosive esophagitis
• Maintenance of healing of erosive esophagitis
• Eradication of Helicobacter pylori infection in patients with duodenal ulcer disease
• Treatment for Zollinger-Ellison Syndrome
• Management of acid-related Dyspepsia
• Treatment for Duodenal & Gastric ulcers

Pharmacology

• Proton pump inhibitor
• Suppresses gastric acid secretion
• Enteric-coated pellet formulation of esomeprazole magnesium
• Metabolized in the liver by the cytochrome P450 (CYP) enzyme system
• Extensively metabolized in the liver
• Plasma elimination half-life of approximately 1–1.5 hours

Dosage

• Oral dosage form
• IV Injection or IV infusion for specific conditions
• Dosage varies for different indications and patient groups
• Recommended duration of treatment for different conditions
• Instructions for oral suspension administration

Administration

• Tablet or capsule should be swallowed whole and taken one hour before a meal
• Oral suspension administration instructions
• IV injection preparation and administration guidelines

Interaction

• Metabolized in the liver by CYP2C19 and CYP3A4
• Potential interference with certain drugs metabolized by CYP2C19
• Possible impact on the absorption of drugs influenced by gastric pH
• No significant interactions with specified drugs

Contraindications

• Contraindicated in patients with known hypersensitivity to any of the formulation

Side effects

• Common adverse events include headache, diarrhea, nausea, flatulence, abdominal pain, constipation, and dry mouth

Pregnancy and lactation

• No adequate and well-controlled studies in pregnant women
• No teratogenic effects observed in animal studies
• Excretion in milk not studied
• Breastfeeding should be discontinued if the use of esomeprazole is considered essential

Precautions and warnings

• Symptomatic response to therapy does not preclude the presence of gastric malignancy
• Specific instructions for patients with difficulty swallowing capsules
• Use of antacids while taking Esotid is permissible

Use in special populations

• Safety and effectiveness in pediatric patients have not been established
• No overall differences in safety and efficacy observed between the elderly and younger individuals
• No dosage adjustment recommended for patients with mild to moderate hepatic insufficiency
• Pharmacokinetics not expected to be altered in patients with renal impairment

Overdose effects

• Signs of acute toxicity observed in animal studies
• No specific antidote known
• Symptomatic and supportive treatment recommended
• Possibility of multiple drug ingestion should be considered

Storage conditions

• Store at a temperature not exceeding 30°C in a dry place
• Protect from light and moisture
• Keep out of reach of children

Chemical structure

• Molecular Formula: C17H19N3O3S
• Chemical Structure represented by an image

Commonly asked questions

• Overview of Esotid 40 mg Capsule
• Multiple uses of Esotid 40 mg Capsule
• Common side effects of Esotid 40 mg Capsule
• Usage of Esotid 40 mg Capsule during pregnancy and breastfeeding
• Duration for Esotid 40 mg Capsule to take effect
• Additional quick tips for using Esotid 40 mg Capsule

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