Esru 20 mg (Tablet (Enteric Coated))

Unit Price: ৳ 4.00 (5 x 10: ৳ 200.00)
Strip Price: ৳ 40.00

Medicine Details

Category Details
Generic Esomeprazole
Company Doctors chemical works ltd

Indications

  • Relief from chronic heartburn symptoms and other symptoms associated with GERD
  • Healing of erosive esophagitis
  • Maintenance of healing of erosive esophagitis
  • Eradication of Helicobacter pylori infection in patients with duodenal ulcer disease
  • Zollinger-Ellison Syndrome
  • Acid related Dyspepsia
  • Duodenal & Gastric ulcer

Pharmacology

  • Proton pump inhibitor
  • Suppresses gastric acid secretion
  • Specific inhibition of the H+/K+-ATPase
  • Better acid control than racemic proton pump inhibitors
  • Enteric-coated pellet formulation
  • Absorption peak at approximately 1.5 hours
  • Metabolized in the liver by cytochrome P450 enzyme system
  • Extensively metabolized in the liver
  • Plasma protein binding is constant over the concentration range
  • Plasma elimination half-life is approximately 1–1.5 hours

Dosage

  • Oral dosage form
  • Healing of Erosive Esophagitis: 20 mg or 40 mg Once Daily for 4-8 Weeks
  • Symptomatic GERD: 20 mg Once Daily for 4 Weeks
  • Helicobacter Pylori eradication: Triple Therapy for 10 days
  • IV Injection for adult and pediatric patients
  • Risk reduction of rebleeding of Gastric or Duodenal Ulcers following therapeutic endoscopy in adults

Administration

  • Tablet or capsule should be swallowed whole and taken one hour before a meal
  • Oral Suspension and IV Injection instructions

Interaction

  • Extensively metabolized in the liver by CYP2C19 and CYP3A4
  • No clinically relevant interactions with drugs metabolized by CYP enzymes
  • Potential interference with CYP2C19
  • Inhibition of gastric acid secretion may interfere with drug absorption

Contraindications

  • Known hypersensitivity to any of the formulation

Side Effects

  • Headache
  • Diarrhea
  • Nausea
  • Flatulence
  • Abdominal pain
  • Constipation
  • Dry mouth

Pregnancy & Lactation

  • No adequate and well-controlled studies in pregnant women
  • Animal studies have revealed no teratogenic effects
  • Excretion of esomeprazole in milk has not been studied
  • Breast-feeding should be discontinued if the use of esomeprazole is considered essential

Precautions & Warnings

  • Symptomatic response to therapy does not preclude the presence of gastric malignancy
  • Instructions for patients
  • Use in Special Populations: Paediatric, Geriatric, Hepatic Insufficiency, Renal Insufficiency

Overdose Effects

  • Acute toxicity signs in rats
  • No specific antidote known
  • Symptomatic and supportive treatment is recommended

Storage Conditions

  • Store at a temperature not exceeding 30°C in a dry place
  • Protect from light and moisture
  • Keep out of reach of children

Chemical Structure

  • Molecular Formula: C17H19N3O3S
  • Chemical Structure

Common Questions

  • What is Esru 20 mg Tablet?
  • What is Esru 20 mg Tablet used for?
  • What are the side effects of Esru 20 mg Tablet?
  • Pregnancy and breastfeeding concerns
  • Duration for Esru 20 mg Tablet to work
  • Quick Tips

Related Brands