NexCap 20 mg (Capsule (Enteric Coated))

Unit Price: ৳ 7.00 (10 x 10: ৳ 700.00)
Strip Price: ৳ 70.00

Medicine Details

Category Details
Generic Esomeprazole
Company Unimed unihealth pharmaceuticals ltd
Also available as
Nexcap 40 mg capsule

Title

  • NexCap 20 mg Capsule

Categories

  • Proton Pump Inhibitor
  • Medication
  • Gastrointestinal Health

Description

  • Relieves chronic heartburn
  • Heals erosive esophagitis
  • Maintains healing of erosive esophagitis
  • Combats Helicobacter pylori infection
  • Treats Zollinger-Ellison Syndrome
  • Addresses Acid-related Dyspepsia
  • Manages Duodenal & Gastric ulcers
  • Provides symptom relief for GERD

DosageForm

Oral tablet, Oral suspension, IV Injection

DosageInstructions

  • 20 mg or 40 mg for erosive esophagitis
  • 20 mg for maintenance of healing
  • 20 mg for symptomatic GERD
  • 40 mg for Helicobacter Pylori eradication
  • 20-80 mg for Zollinger-Ellison Syndrome
  • 20-40 mg for Acid-related Dyspepsia
  • 20 mg for Duodenal ulcer
  • 20-40 mg for Gastric ulcer

AdministrationInstructions

  • Tablet or capsule should be swallowed whole and taken one hour before a meal
  • Oral suspension to be mixed with water and taken within 30 minutes
  • IV Injection to be administered over a specific time period

Pharmacology

  • MechanismOfAction: Suppression of gastric acid secretion
  • Absorption: Enteric-coated pellet formulation of esomeprazole magnesium
  • Distribution: Approximately 97% bound to plasma proteins
  • Metabolism: Extensive liver metabolism via CYP enzyme system
  • Excretion: Less than 1% excreted in urine

Interaction

  • MetabolizingEnzymes: CYP2C19 and CYP3A4
  • InhibitoryEffects: Not expected to inhibit CYPs 1A2, 2A6, 2C9, 2D6, 2E1 and 3A4
  • ClinicallyRelevantInteractions: None with phenytoin, warfarin, quinidine, clarithromycin, or amoxicillin
  • PotentialInteractions:
    • Diazepam
    • Ketoconazole
    • Iron salts
    • Digoxin

Contraindications

  • Known hypersensitivity to any of the formulation

SideEffects

  • Headache
  • Diarrhea
  • Nausea
  • Flatulence
  • Abdominal pain
  • Constipation
  • Dry mouth

PregnancyAndLactation

No adequate studies in pregnant women, excretion in milk not studied, breast-feeding should be discontinued if essential

PrecautionsAndWarnings

  • General: Symptomatic response does not preclude presence of gastric malignancy
  • AdministrationAdvice: Capsules can be opened and mixed with applesauce for swallowing

SpecialPopulations

  • PaediatricUse: Safety and effectiveness not established
  • GeriatricUse: No overall differences in safety and efficacy observed
  • HepaticInsufficiency: No dosage adjustment for mild to moderate insufficiency
  • RenalInsufficiency: Pharmacokinetics not expected to be altered

OverdoseEffects

  • LethalDose: 510 mg/kg in rats
  • SignsOfToxicity:
    • Reduced motor activity
    • Tremor
    • Clonic convulsions
  • Antidote: No specific antidote known, treatment should be symptomatic and supportive

StorageConditions

Store at a temperature not exceeding 30°C, protect from light and moisture, keep out of reach of children

ChemicalStructure

  • MolecularFormula: C17H19N3O3S
  • ChemicalStructureImage: https://medex.com.bd/storage/res/g-res-433-esomeprazole-chemical-structure-Tj2Jfp1VmPkRjNXznKqC.svg

CommonlyAskedQuestions

  • What is NexCap 20 mg Capsule?
  • What is NexCap 20 mg Capsule used for?
  • What are the side effects of NexCap 20 mg Capsule?
  • Can I take NexCap 20 mg Capsule if I am pregnant or breastfeeding?
  • How long does it take for NexCap 20 mg Capsule to work?

QuickTips

  • NexCap 20 mg Capsule is well-tolerated
  • Avoid eating late at night or before bedtime
  • Inform your doctor about unusual symptoms

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