Nexe 40 mg (Capsule (Enteric Coated))

Unit Price: ৳ 9.00 (6 x 10: ৳ 540.00)
Strip Price: ৳ 90.00

Medicine Details

Category Details
Generic Esomeprazole
Company Apex pharmaceuticals ltd
Also available as
Nexe 20 mg tablet Nexe 20 mg capsule Nexe 40 mg injection

Title

  • Nexe 40 mg Capsule

Categories

  • Medicine
  • Health & Wellness

Indications

  • Relief from chronic heartburn symptoms
  • Healing of erosive esophagitis
  • Maintenance of healing of erosive esophagitis
  • Eradication of Helicobacter pylori infection in patients with duodenal ulcer disease
  • Zollinger-Ellison Syndrome
  • Acid-related Dyspepsia
  • Treatment of Duodenal and Gastric ulcer

DosageForms

  • Tablet
  • Capsule
  • Oral Suspension
  • IV Injection
  • IV Infusion

Dosage

  • 20 mg or 40 mg Once Daily for Healing of Erosive Esophagitis
  • 20 mg Once Daily for Maintenance of Healing of Erosive Esophagitis
  • 20 mg Once Daily for Symptomatic GERD
  • Triple Therapy for Helicobacter Pylori eradication
  • 20-80 mg Once Daily for Zollinger-Ellison Syndrome
  • 20-40 mg Once Daily for Acid-related Dyspepsia
  • 20 mg Once Daily for 2-4 weeks for Duodenal ulcer
  • 20-40 mg Once Daily for 4-8 weeks for Gastric ulcer
  • IV Injection or IV Infusion for GERD with Erosive Esophagitis and Risk reduction of rebleeding of Gastric or Duodenal Ulcers

Administration

  • Tablet or capsule should be swallowed whole and taken one hour before a meal
  • Oral Suspension should be mixed with water and consumed within 30 minutes
  • IV Injection should be given over a period of at least 3 minutes

Interaction

  • Metabolized in the liver by CYP2C19 and CYP3A4
  • No clinically significant interactions with certain CYP enzymes
  • Potential interference with drugs affected by gastric pH

Contraindications

  • Known hypersensitivity to any of the formulation

SideEffects

  • Headache
  • Diarrhoea
  • Nausea
  • Flatulence
  • Abdominal pain
  • Constipation
  • Dry mouth

PregnancyLactation

  • No adequate and well-controlled studies in pregnant women
  • Animal studies show no teratogenic effects
  • Excretion in milk not studied
  • Breastfeeding should be discontinued if essential

PrecautionsWarnings

  • Symptomatic response to therapy does not preclude the presence of gastric malignancy
  • Instructions for patients
  • Use of antacids is permitted

SpecialPopulations

  • Safety and effectiveness not established in paediatric patients
  • No overall differences in safety and efficacy observed between elderly and younger individuals
  • No dosage adjustment recommended for patients with mild to moderate hepatic insufficiency
  • Pharmacokinetics not expected to be altered in renal impairment

OverdoseEffects

  • Acute toxicity in rats at high doses
  • No specific antidote known
  • Treatment should be symptomatic and supportive

StorageConditions

  • Store at a temperature not exceeding 30°C
  • Protect from light and moisture
  • Keep out of reach of children

ChemicalStructure

  • Molecular Formula: C17H19N3O3S
  • Chemical Structure Image: (URL to image)

CommonQuestions

  • Uses of Nexe 40 mg Capsule
  • Side effects of Nexe 40 mg Capsule
  • Safety during pregnancy and breastfeeding
  • Onset of action
  • Quick tips for consumption

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