Opton 20 mg (Tablet (Enteric Coated))

Unit Price: ৳ 5.00 (10 x 10: ৳ 500.00)
Strip Price: ৳ 50.00

Medicine Details

Category Details
Generic Esomeprazole
Company Beximco pharmaceuticals ltd
Also available as
Opton 40 mg tablet Opton 20 mg capsule Opton 40 mg capsule

Indications

  • Relief from chronic heartburn symptoms
  • Healing of erosive esophagitis
  • Maintenance of healing of erosive esophagitis
  • Eradication of Helicobacter pylori infection
  • Treatment for Zollinger-Ellison Syndrome
  • Management of acid-related Dyspepsia
  • Healing of Duodenal & Gastric ulcer

Pharmacology

  • Proton pump inhibitor
  • Suppression of gastric acid secretion
  • Specific inhibition of the H+/K+-ATPase
  • Single optical isomer providing better acid control
  • Enteric-coated pellet formulation
  • Peak plasma levels at approximately 1.5 hours after oral administration

Dosage

  • 20 mg or 40 mg Once Daily for 4-8 Weeks to heal erosive esophagitis
  • 20 mg Once Daily for maintenance of healing of erosive esophagitis
  • 20 mg Once Daily for symptomatic GERD
  • Triple Therapy for Helicobacter pylori eradication
  • 20-80 mg Once Daily for Zollinger-Ellison Syndrome
  • 20-40 mg Once Daily for acid-related Dyspepsia

Administration

  • Tablet or capsule should be swallowed whole and taken one hour before a meal
  • Oral Suspension should be stirred well and drunk within 30 minutes
  • IV Injection or IV infusion under specific dosages for different conditions

Interaction

  • Metabolized in the liver by CYP2C19 and CYP3A4
  • No clinically significant interactions with specific drugs
  • Potential interference with CYP2C19 and absorption of certain drugs

Contraindications

  • Contraindicated in patients with known hypersensitivity to any of the formulation

Side Effects

  • Headache
  • Diarrhoea
  • Nausea
  • Flatulence
  • Abdominal pain
  • Constipation
  • Dry mouth

Pregnancy & Lactation

  • No adequate and well-controlled studies in pregnant women
  • No excretion of esomeprazole in milk studied
  • Recommended to discontinue breastfeeding if esomeprazole use is essential

Precautions & Warnings

  • Symptomatic response to therapy does not preclude the presence of gastric malignancy
  • Special instructions for patients who have difficulty swallowing capsules
  • Use of antacids while taking the product

Use in Special Populations

  • Safety and effectiveness in paediatric patients not established
  • No differences in safety and efficacy in the elderly
  • No dosage adjustment recommended for patients with mild to moderate hepatic insufficiency

Overdose Effects

  • Acute toxicity signs in animal studies
  • No specific antidote known
  • Symptomatic and supportive treatment in case of overdose

Storage Conditions

  • Store at a temperature not exceeding 30°C in a dry place
  • Protect from light and moisture
  • Keep out of reach of children

Chemical Structure

  • Molecular Formula: C17H19N3O3S
  • Chemical Structure Image Available

Common Questions about Opton 20 mg Tablet

  • Purpose of Opton 20 mg Tablet
  • Multiple uses including treatment for GERD and ulcers
  • Common side effects such as headaches and stomach discomfort
  • Safety of use during pregnancy and breastfeeding
  • Expected time for Opton 20 mg Tablet to begin working
  • Quick Tips for using Opton 20 mg Tablet

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