Domin 15 mg (Suppository)

Unit Price: ৳ 5.02 (2 x 5: ৳ 50.20)

Medicine Details

Category Details
Generic Domperidone maleate
Company Opsonin pharma ltd
Also available as
Domin 10 mg tablet Domin 5 mg suspension Domin 5 mg pediatric drop Domin 30 mg suppository

Title

Domin 15 mg Suppository

Categories

  • Medicine
  • Gastrointestinal Health
  • Nausea Relief

Description

Domin 15 mg Suppository is a dopamine antagonist medication used to treat dyspeptic symptom complex, acute nausea and vomiting, Parkinson's disease, and for speeding barium transit in radiological studies.

Dimensions

Rectal suppository

Color Options

  • White

Functions

  • Relieves dyspeptic symptoms
  • Controls acute nausea and vomiting
  • Aids in Parkinson's disease
  • Facilitates barium transit in radiological studies

Materials

Domperidone

Technical Specifications

  • Dosage and Administration:
    • Adults: 10-20 mg every 6-8 hours daily (maximum 80 mg daily)
    • Children: 2-4 ml suspension/10 kg body weight every 6-8 hours daily
    • Route:
      • Oral
      • Rectal
  • Interaction:
    • Contraindications: Anticholinergic drugs may antagonize the antidyspeptic effect, not to be given simultaneously with antacids and antisecretory drugs; metabolism through CYP3A4; potential inhibition of orally administered drugs
  • Pregnancy & Lactation: Use during the first trimester of pregnancy with caution; excreted in breast milk, lower concentrations than plasma

Design Elements

  • Suppository form
  • Packaging design

Usability Features

  • Prevents regurgitation of gastric content
  • Enhances antral and duodenal peristalsis
  • Regulates contraction of the pylorus
  • Increases esophageal peristalsis

Contraindications

  • Known Hypersensitivity: Contraindicated
  • Neonates: Contraindicated
  • Gastrointestinal Stimulation: Contraindicated in dangerous conditions such as hemorrhage, obstruction, perforation
  • Prolactin Releasing Pituitary Tumor: Contraindicated

Side Effects

  • Common:
    • Transient intestinal cramps
  • Rare:
    • Extrapyramidal phenomena
    • Hyperprolactinemia-related effects such as galactorrhea and gynecomastia
    • Allergic reactions like rash and urticaria

Precautions & Warnings

  • Children: Use with caution due to increased risk of extrapyramidal reactions
  • Hepatic Impairment: Use with caution due to highly metabolized in the liver

Special Populations

  • Infants: Should be given with great caution and under close medical supervision
  • Liver Disorders: Use with caution
  • Kidney Disorders: Consider dose adjustment in severe renal insufficiency

Overdose Effects

  • Drowsiness
  • Disorientation
  • Extrapyramidal reactions

Therapeutic Class

Motility Stimulants/Dopamine Antagonist/Prokinetic Drugs

Storage Conditions

Below 30°C, Protected from light & moisture

Chemical Structure

  • Molecular Formula: C22H24ClN5O2

Common Questions

  • Uses: Treats nausea and vomiting
  • Quick Tips:
    • Helps relieve nausea, vomiting, and indigestion
    • May cause dizziness and sleepiness
    • Avoid alcohol consumption
    • Inform the doctor about persistent symptoms
    • Consult the doctor for prolonged use

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