Esogap 20 mg (Capsule (Enteric Coated))

Unit Price: ৳ 7.00 (10 x 10: ৳ 700.00)
Strip Price: ৳ 70.00

Medicine Details

Category Details
Generic Esomeprazole
Company Euro pharma ltd
Also available as
Esogap 20 mg tablet Esogap 40 mg tablet Esogap 40 mg capsule Esogap 40 mg injection

Indications

  • Relief from chronic heartburn symptoms and other symptoms associated with GERD
  • Healing of erosive esophagitis
  • Maintenance of healing of erosive esophagitis
  • Eradication of Helicobacter pylori infection in patients with duodenal ulcer disease
  • Treatment of Zollinger-Ellison Syndrome
  • Treatment of Acid-related Dyspepsia
  • Treatment of Duodenal & Gastric ulcer

Pharmacology

  • Proton pump inhibitor
  • Suppresses gastric acid secretion
  • Inhibits the H+/K+-ATPase in the gastric parietal cell
  • Better acid control than racemic proton pump inhibitors
  • Enteric-coated pellet formulation
  • Peak plasma levels occur at approximately 1.5 hours
  • Extensively metabolized in the liver
  • Plasma elimination half-life is approximately 1-1.5 hours

Dosage

  • Dosage forms include tablets, capsules, and IV injections
  • Various dosages for different conditions
  • Dosage adjustments for pediatric patients
  • Duration of treatment specified for each condition

Administration

  • Tablet or capsule should be swallowed whole
  • Oral suspension instructions for preparation and administration
  • IV injection instructions for preparation and administration

Interaction

  • Metabolized by CYP2C19 and CYP3A4
  • No clinically significant interactions with certain drugs
  • Potential interference with CYP2C19
  • Possible interference with the absorption of certain drugs

Contraindications

  • Contraindicated in patients with known hypersensitivity to any of the formulation

Side Effects

  • Common adverse events include headache, diarrhea, nausea, flatulence, abdominal pain, constipation, dry mouth

Pregnancy & Lactation

  • No adequate and well-controlled studies in pregnant women
  • No teratogenic effects observed in animal studies
  • Breastfeeding should be discontinued if esomeprazole use is essential

Precautions & Warnings

  • Symptomatic response to therapy does not preclude the presence of gastric malignancy
  • Instructions for patients on capsule administration
  • Use of antacids while taking esomeprazole

Use in Special Populations

  • No established safety and effectiveness in pediatric patients
  • No overall differences in safety and efficacy observed in geriatric use
  • No dosage adjustment recommended for patients with mild to moderate hepatic insufficiency
  • No alteration in pharmacokinetics in patients with renal impairment

Overdose Effects

  • Acute toxicity signs include reduced motor activity, changes in respiratory frequency, tremor, ataxia, and convulsions
  • No specific antidote for esomeprazole
  • Treatment should be symptomatic and supportive

Storage Conditions

  • Store at a temperature not exceeding 30°C
  • Protect from light and moisture
  • Keep out of reach of children

Chemical Structure

  • Molecular Formula: C17H19N3O3S
  • Image of the chemical structure provided

Common Questions about Esogap 20 mg Capsule

  • Description of Esogap as a proton pump inhibitor
  • Uses of Esogap for various conditions
  • Common side effects of Esogap 20 mg Capsule
  • Guidance on use during pregnancy and breastfeeding
  • Onset of action and quick tips for usage

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