Albendox 400 mg (Chewable Tablet)

Unit Price: ৳ 4.00 (50's pack: ৳ 200.00)

Medicine Details

Category Details
Generic Albendazole
Company Indo bangla pharmaceutical

Indications

  • Single and mixed infestations of hookworm, roundworm, threadworm, whipworm, strongyloides, tapeworm, opisthorchi, hydatid

Description

  • Benzimidazole anthelmintic
  • Active against most nematodes and some cestodes
  • Used in the treatment of intestinal nematode infections and hydatid disease
  • Vermicidal, ovicidal, and larvicidal activity
  • Inhibitory effect on tubulin polymerization

Pharmacology

  • Broad spectrum anthelmintic
  • Exhibits vermicidal, ovicidal, and larvicidal activities
  • Blocks glucose uptake in susceptible helminths
  • Depletes energy level leading to immobilization of parasites
  • Extensively metabolized, primarily in the liver
  • Poorly absorbed from the gastrointestinal tract

Dosage & Administration

  • 400 mg single dose for adults and children over 2 years in certain infections
  • 400 mg daily for 3 consecutive days in cases of strongyloidiasis or taeniasis
  • 200 mg single dose for children of 1-2 years
  • Not recommended for children under 1 year
  • 400 mg twice daily for 28 days for patients weighing over 60 kg in hydatid disease
  • 15 mg/kg body weight daily in two divided doses for patients weighing less than 60 kg in hydatid disease
  • 400 mg once daily for five days in giardiasis

Interaction

  • No reported pharmacodynamic or pharmacokinetic interactions

Contraindications

  • Not normally used in neonates
  • Possible dose reduction in children weighing less than 10 kg
  • Not recommended during pregnancy or for women thought to be pregnant
  • No evidence to suggest dose alteration in renal, hepatic, or cardiac failure

Side Effects

  • Gastrointestinal disturbances, headache, dizziness
  • Changes in liver enzymes, reversible alopecia
  • Rash, fever, blood disorders including leucopenia and pancytopenia
  • Allergic shock if cyst leakage
  • Convulsion and meningism in cerebral disease

Pregnancy & Lactation

  • Should be avoided in pregnancy and lactation unless benefits outweigh risks
  • US FDA Pregnancy category C

Precautions & Warnings

  • Blood counts and liver function tests before treatment and during each cycle
  • Breastfeeding
  • Exclude pregnancy before starting treatment
  • Use with constant medical supervision in treatment of Echinococcosis

Therapeutic Class

  • Anthelmintic

Storage Conditions

  • Keep in a dry place, away from light and heat
  • Keep out of the reach of children

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