Esonix 20 mg/vial (IV Injection)
20 mg vial: ৳ 110.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Esomeprazole |
| Company | Incepta pharmaceuticals ltd |
| Also available as |
Indications
- Relief from chronic heartburn symptoms
- Healing of erosive esophagitis
- Maintenance of healing of erosive esophagitis
- Eradication of Helicobacter pylori infection
- Treatment of Zollinger-Ellison Syndrome
- Management of Acid related Dyspepsia
- Healing of Duodenal & Gastric ulcers
Pharmacology
- Proton pump inhibitor
- Suppresses gastric acid secretion
- Specific inhibition of the H+/K+-ATPase
- First single optical isomer of proton pump inhibitor
- Provides better acid control than racemic proton pump inhibitors
- Rapid absorption after oral administration
- Extensive metabolism in the liver
- Low plasma elimination half-life
- Extensively bound to plasma proteins
Dosage
- Multiple dosage forms - oral, IV injection, IV infusion
- Different dosages for various indications and patient groups
- Recommendations for adult and pediatric patients
- Instructions for dosage adjustment based on conditions
Administration
- Tablet or capsule should be swallowed whole
- Instructions for oral suspension preparation and administration
- Guidelines for IV injection and infusion preparation and administration
Interaction
- Extensive metabolism by CYP2C19 and CYP3A4
- Inhibition of specific CYP enzymes
- Potential interference with drug absorption
Contraindications
- Known hypersensitivity to the formulation
Side Effects
- Frequently occurring adverse events like headache, diarrhea, nausea, etc.
- Similar adverse events during short term and maintenance treatment
Pregnancy & Lactation
- No adequate and well-controlled studies in pregnant women
- No teratogenic effects in animal studies
- Lack of information on excretion in milk
Precautions & Warnings
- Symptomatic response does not rule out gastric malignancy
- Special instructions for patients with difficulty swallowing capsules
- Allowance for use of antacids alongside esomeprazole
Use in Special Populations
- Lack of established safety and effectiveness in pediatric patients
- No overall differences in safety and efficacy in geriatric use
- Guidance for dosage adjustment in hepatic and renal insufficiency
Overdose Effects
- Lethal dose in animal studies
- Major signs of acute toxicity
- No specific antidote known
- Symptomatic and supportive treatment recommended
Storage Conditions
- Temperature and environmental precautions
Chemical Structure
- Molecular formula: C17H19N3O3S
- Illustration of chemical structure
Common Questions
- General information about esomeprazole
- Specific uses of esomeprazole
- Details on side effects
- Safety considerations during pregnancy and breastfeeding
- Expected time for esomeprazole to work
- Quick tips for users