Ema 20 mg (Capsule (Enteric Coated))
Medicine Details
Category | Details |
---|---|
Generic | Esomeprazole |
Company | Globe pharmaceuticals ltd |
Also available as |
Title
Ema 20 mg Capsule
Categories
- Medicine
- Healthcare
- Pharmaceuticals
Description
Ema 20 mg Capsule is a proton pump inhibitor used to relieve chronic heartburn and symptoms associated with GERD, healing of erosive esophagitis, and maintenance of healing. It can also aid in the eradication of Helicobacter pylori infection, treat Zollinger-Ellison Syndrome, acid-related dyspepsia, and duodenal & gastric ulcers.
DosageOptions
- 20 mg
- 40 mg
AdministrationMethod
- Oral
- IV Injection
- IV Infusion
- Oral Suspension
AbsorptionTime
Approximately 1.5 hours
PlasmaProteinBinding
97%
Metabolism
- Cytochrome P450 enzyme system
- CYP2C19
- CYP3A4
Excretion
- Less than 1% excreted in urine
- 80% excreted as inactive metabolites in urine
CombinationTherapy
- Clarithromycin
- Amoxicillin
- Triple Therapy for Helicobacter pylori eradication
InteractionCYPEnzymes
- CYP2C19
- CYP3A4
Contraindications
Known hypersensitivity to any of the formulation
SideEffects
- Headache
- Diarrhea
- Nausea
- Flatulence
- Abdominal pain
- Constipation
- Dry mouth
PregnancyLactation
No adequate and well-controlled studies in pregnant women, should be discontinued during breastfeeding
PrecautionsAndWarnings
- Symptomatic response does not preclude the presence of gastric malignancy
- Capsules should be taken at least one hour before meals
- Use of antacids permitted
SpecialPopulations
- Paediatric Use
- Geriatric Use
- Hepatic Insufficiency
- Renal Insufficiency
OverdoseEffects
- Reduced motor activity
- Respiratory frequency changes
- Tremor
- Ataxia
- Intermittent clonic convulsions
StorageConditions
- Temperature not exceeding 30°C
- Dry place
- Protected from light and moisture
- Keep out of reach of children
MolecularFormula
C17H19N3O3S
Storage
Store at a temperature not exceeding 30°C in a dry place, protect from light and moisture, keep out of reach of children
CommonlyAskedQuestions
- Uses of Ema 20 mg Capsule
- Side effects of Ema 20 mg Capsule
- Pregnancy and breastfeeding considerations
- Onset of action for Ema 20 mg Capsule
SpecialInstructions
Ema capsules should be taken at least one hour before meals. For patients who have difficulty swallowing capsules, the pellets inside the capsule can be emptied onto applesauce and swallowed immediately without chewing
UseInSpecialPopulations
- Safety and effectiveness in paediatric patients not established
- No overall differences in safety and efficacy between elderly and younger individuals
- No dosage adjustment recommended for mild to moderate hepatic insufficiency
- Pharmacokinetics not expected to be altered in renal impairment
ChemicalStructure
- MolecularFormula: C17H19N3O3S