Esoprex 40 mg/vial (IV Injection)

40 mg vial: ৳ 100.30

Medicine Details

Category Details
Generic Esomeprazole
Company Beacon pharmaceuticals plc
Also available as
Esoprex 20 mg capsule Esoprex 40 mg capsule

Title

Esoprex Medicine

Categories

  • Heartburn Relief
  • GERD Treatment
  • Acid Reducer
  • Ulcer Healing

Description

Esomeprazole is a proton pump inhibitor used for relieving chronic heartburn, healing erosive esophagitis, maintenance of healing of erosive esophagitis, eradication of Helicobacter pylori infection, Zollinger-Ellison Syndrome, acid-related dyspepsia, duodenal & gastric ulcers.

Indications

  • Chronic Heartburn Relief
  • GERD Symptoms Relief
  • Erosive Esophagitis Healing
  • Helicobacter pylori Eradication
  • Zollinger-Ellison Syndrome Treatment
  • Acid-related Dyspepsia Relief
  • Duodenal & Gastric Ulcer Healing

Pharmacology

  • Proton Pump Inhibition
  • Gastric Acid Suppression
  • Absorption
  • Distribution
  • Metabolism
  • Excretion
  • Combination Therapy with Antimicrobials

Dosage

  • 20mg Once Daily for Erosive Esophagitis Healing
  • 20mg Once Daily for Symptomatic GERD
  • 40mg Once Daily for Helicobacter Pylori Eradication
  • 20-80mg Once Daily for Zollinger-Ellison Syndrome
  • 20-40mg Once Daily for Acid-related Dyspepsia
  • 20mg Once Daily for Duodenal Ulcer
  • IV Injection: 20mg or 40mg Once Daily for GERD with Erosive Esophagitis

Administration

  • Swallow Tablet or Capsule Whole
  • Oral Suspension Use
  • IV Injection Preparation & Administration

Interaction

  • Metabolism by CYP2C19 and CYP3A4
  • Potential Interference with CYP2C19
  • Gastric Acid Secretion Inhibition
  • Absorption Interference with Gastric pH-dependent Drugs
  • No Clinically Significant Interactions with Certain Drugs

Contraindications

  • Known Hypersensitivity to Formulation

Side effects

  • Headache
  • Diarrhea
  • Nausea
  • Flatulence
  • Abdominal Pain
  • Constipation
  • Dry Mouth

Pregnancy and lactation

  • No Adequate Studies in Pregnant Women
  • No Teratogenic Effects in Animal Studies
  • Excretion in Milk Not Studied
  • Breastfeeding Discontinuation if Essential

Precautions and warnings

  • Symptomatic Response Does Not Rule Out Gastric Malignancy
  • Administration Instructions
  • Use of Antacids
  • Applesauce Mixing Option for Difficulty in Swallowing Capsules

Special populations

  • Safety and Effectiveness in Paediatric Patients Not Established
  • No Differences in Safety and Efficacy between Elderly and Younger Individuals
  • No Dosage Adjustment for Mild to Moderate Hepatic Insufficiency
  • No Altered Pharmacokinetics in Renal Impairment

Overdose effects

  • Lethal Dose Effects in Rats
  • Symptomatic and Supportive Treatment Recommended in Overdose
  • No Specific Antidote Known
  • Extensive Protein Binding

Storage conditions

  • Store at Temperature Not Exceeding 30°C
  • Protect from Light and Moisture
  • Keep Out of Reach of Children

Chemical structure

  • Molecular Formula: C17H19N3O3S
  • Chemical Structure Image

Commonly asked questions

  • Uses of Esoprex 40mg/vial Injection
  • Side Effects of Esoprex 40mg/vial Injection
  • Pregnancy and Breastfeeding Concerns
  • Onset of Action
  • Quick Tips

Url

https://medex.com.bd/storage/res/g-res-433-esomeprazole-chemical-structure-Tj2Jfp1VmPkRjNXznKqC.svg

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