Perigut 5 mg/5 ml (Oral Suspension)
60 ml bottle: ৳ 28.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Domperidone maleate |
| Company | Leon pharmaceuticals ltd |
| Also available as |
Title
- Perigut 5 mg/5 ml Suspension
Categories
- Gastrointestinal Medication
- Nausea and Vomiting Relief
- Parkinson's Disease Treatment
- Radiological Studies Aid
DosageForm
- Suspension
GenericName
- Domperidone
BrandName
- Perigut
Strength
- 5 mg/5 ml
Indications
- Relief of Dyspeptic Symptoms
- Acute Nausea and Vomiting
- Parkinson's Disease-Induced Nausea
- Speeding Barium Transit in Radiological Studies
Pharmacology
- Dopamine Antagonist
- Gastroprokinetic Action
- Restores Normal Gastrointestinal Motility
- Enhances Gastric Emptying
- Regulates Esophageal Peristalsis
- Increases Lower Esophageal Sphincter Pressure
DosageAndAdministration
- Should be taken 15-30 minutes before meals
- Adults: 10-20 mg (1-2 tablets or 10-20 ml suspension) every 6-8 hours daily
- Children: Dosage based on body weight and condition
Interaction
- Concomitant use of anticholinergic drugs may antagonize domperidone's effect
- Avoid simultaneous administration with antacids and antisecretory drugs
- Metabolized through CYP3A4 pathway
- May interact with CYP3A4 inhibitors and drugs
Contraindications
- Known hypersensitivity to domperidone
- Neonates
- Conditions of dangerous gastrointestinal stimulation
- Prolactin Releasing Pituitary Tumor
SideEffects
- Rare occurrence of transient intestinal cramps
- Rare extrapyramidal phenomena
- Potential increase in plasma prolactin level
- Rare allergic reactions such as rash and urticaria
PregnancyAndLactation
- Use in first trimester of pregnancy if justified by therapeutic benefit
- No evidence of increased risk of malformations in humans
- Domperidone excreted in breast milk
- Nursing not recommended unless expected benefits outweigh potential risk
PrecautionsAndWarnings
- Increased risk of extra-pyramidal reactions in young children
- Caution in patients with hepatic impairment
- Use in infants and special populations
- Review of patients on prolonged therapy
OverdoseEffects
- Symptoms may include drowsiness, disorientation, and extrapyramidal reactions
- Recommendation of activated charcoal administration and close observation
TherapeuticClass
- Motility Stimulants
- Dopamine Antagonist
- Prokinetic Drugs
StorageConditions
- Store below 30°C
- Protected from light and moisture
- Keep out of children's reach
ChemicalStructure
- Molecular Formula: C22H24ClN5O2
- Chemical Structure Image URL
FAQ
- Usage for Nausea and Vomiting Relief
- Quick Tips for Perigut 5 mg/5 ml Suspension