Benidon 5 mg/5 ml (Oral Suspension)

60 ml bottle: ৳ 35.00

Medicine Details

Category Details
Generic Domperidone maleate
Company Benham pharmaceuticals ltd
Also available as

Title

  • Benidon 5 mg/5 ml Suspension

Categories

  • Medicine
  • Pharmaceutical

Description

  • Dopamine antagonist medication for the treatment of dyspeptic symptom complex, nausea, and vomiting

Formulation

  • Suspension

DosageStrength

  • 5 mg/5 ml

Indications

  • Epigastric sense of fullness
  • Abdominal distension
  • Upper abdominal pain
  • Eructation
  • Flatulence
  • Early satiety
  • Nausea
  • Vomiting
  • Heartburn
  • Non-ulcer dyspepsia
  • Acute nausea
  • Functional nausea
  • Organic nausea
  • Infectious nausea
  • Dietetic-induced nausea
  • Nausea induced by radiotherapy
  • Nausea induced by drug therapy
  • Nausea induced in migraine
  • Parkinson's disease-induced nausea and vomiting
  • Radiological studies for speeding barium transit

Pharmacology

  • Dopamine antagonist
  • Gastroprokinetic action
  • Blocks dopamine receptors in CTZ and stomach
  • Restores normal motility and tone of upper gastrointestinal tract

DosageAdministration

  • RecommendedDose: 10-20 mg for adults
  • DosageFrequency: Every 6-8 hours daily
  • MaximumDose: 80 mg daily
  • ChildrenDose: 2-4 ml suspension/10 kg body weight
  • RectalDosage: 30-60 mg every 4-8 hours for adults

Interaction

  • Anticholinergic drugs may antagonize the antidyspeptic effect
  • Concomitant use with CYP3A4 inhibitors may increase plasma levels of domperidone

Contraindications

  • Known hypersensitivity to domperidone
  • Neonates
  • Gastrointestinal hemorrhage
  • Mechanical obstruction or perforation
  • Prolactin releasing pituitary tumor

SideEffects

  • Transient intestinal cramps
  • Extrapyramidal phenomena
  • Galactorrhea
  • Gynecomastia
  • Allergic reactions such as rash and urticaria

PregnancyLactation

  • Use in the first trimester of pregnancy if justified by therapeutic benefit
  • Not recommended during nursing

PrecautionsWarnings

  • Caution in children due to risk of extra-pyramidal reactions
  • Caution in hepatic impairment

SpecialPopulations

  • Use in infants with caution and close medical supervision
  • Use in liver disorders with caution
  • Dosing adjustment in severe renal insufficiency

OverdoseEffects

  • Drowsiness
  • Disorientation
  • Extrapyramidal reactions

TherapeuticClass

  • Motility Stimulants
  • Dopamine antagonist
  • Prokinetic drugs

StorageConditions

  • Store below 30°C
  • Protected from light and moisture
  • Keep out of children's reach

ChemicalStructure

  • MolecularFormula: C22H24ClN5O2
  • StructureImage: https://medex.com.bd/storage/res/g-res-380-domperidone-maleate-chemical-structure-4Q6P0Z8laWrV7xnOkSMm.svg

CommonQuestions

  • Used for treating nausea and vomiting
  • Helps relieve nausea, vomiting, and indigestion
  • Should be taken before meals as per doctor's prescription
  • May cause dizziness and sleepiness
  • Avoid alcohol consumption
  • Inform doctor if experiencing specific symptoms
  • Do not exceed 7 days of usage without consulting doctor

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