Staflu 125 mg/5 ml (Powder for Suspension)

100 ml bottle: ৳ 65.20

Medicine Details

Indications

  • Skin and soft tissue infections
  • Respiratory tract infections
  • Osteomyelitis
  • Enteritis
  • Endocarditis
  • Urinary tract infections
  • Meningitis
  • Septicaemia
  • Prophylactic use in surgery

Pharmacology

  • Active against Gram-positive organisms
  • Little activity against Gram-negative bacilli
  • Inhibits formation of bacterial cell wall
  • Bactericidal antibiotic
    • Mechanism of action: Inhibits transpeptidase enzyme, weakens cell wall, causes cell rupture
    • Properties: Resistance to hydrolysis by penicillinase, gastric acid stability

Dosage

  • Oral administration for adults and children
  • Parenteral administration for adult, elderly, and children
  • Dosage adjustment for severe infections
  • Dosing frequency and interval

Administration

  • Oral doses to be taken 1 hour before meal

Interaction

  • Concurrent use may increase blood levels of Staflu

Contraindications

  • Contraindicated in penicillin hypersensitive patients

Side Effects

  • Common gastrointestinal side effects
  • Rashes
  • Urticaria
  • Purpura
  • Fever
  • Interstitial nephritis
  • Hepatitis
  • Cholestatic jaundice

Pregnancy & Lactation

  • US FDA Pregnancy Category B
  • Caution during pregnancy
  • Excreted in human milk
  • Caution during lactation

Precautions & Warnings

  • Caution in patients with hepatic dysfunction
  • Caution in patients with allergic diathesis

Use in Special Populations

  • Caution in severe renal failure

Therapeutic Class

  • Penicillinase-resistant penicillins

Reconstitution

  • Use in other routes in conjunction with systemic therapy
  • Administration by intraarticular and intrapleural injection
  • Inhalation by nebuliser

Storage Conditions

  • Keep in dry place
  • Keep away from light and heat
  • Keep out of the reach of children

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