Staflu 125 mg/5 ml (Powder for Suspension)
100 ml bottle: ৳ 65.20
Medicine Details
Category | Details |
---|---|
Generic | Flucloxacillin sodium |
Company | Alco pharma ltd |
Also available as |
Indications
- Skin and soft tissue infections
- Respiratory tract infections
- Osteomyelitis
- Enteritis
- Endocarditis
- Urinary tract infections
- Meningitis
- Septicaemia
- Prophylactic use in surgery
Pharmacology
- Active against Gram-positive organisms
- Little activity against Gram-negative bacilli
- Inhibits formation of bacterial cell wall
- Bactericidal antibiotic
- Mechanism of action: Inhibits transpeptidase enzyme, weakens cell wall, causes cell rupture
- Properties: Resistance to hydrolysis by penicillinase, gastric acid stability
Dosage
- Oral administration for adults and children
- Parenteral administration for adult, elderly, and children
- Dosage adjustment for severe infections
- Dosing frequency and interval
Administration
- Oral doses to be taken 1 hour before meal
Interaction
- Concurrent use may increase blood levels of Staflu
Contraindications
- Contraindicated in penicillin hypersensitive patients
Side Effects
- Common gastrointestinal side effects
- Rashes
- Urticaria
- Purpura
- Fever
- Interstitial nephritis
- Hepatitis
- Cholestatic jaundice
Pregnancy & Lactation
- US FDA Pregnancy Category B
- Caution during pregnancy
- Excreted in human milk
- Caution during lactation
Precautions & Warnings
- Caution in patients with hepatic dysfunction
- Caution in patients with allergic diathesis
Use in Special Populations
- Caution in severe renal failure
Therapeutic Class
- Penicillinase-resistant penicillins
Reconstitution
- Use in other routes in conjunction with systemic therapy
- Administration by intraarticular and intrapleural injection
- Inhalation by nebuliser
Storage Conditions
- Keep in dry place
- Keep away from light and heat
- Keep out of the reach of children